Intermediates

2-Amino-4-chloropyrimidine

  • CAS No.3993-78-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Amino-4-chloropyrimidine (CAS 3993-78-0) designed for pharmaceutical synthesis. Ideal intermediate for antiretroviral drug production with strict quality control.

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Product Technical Details

Product Overview

2-Amino-4-chloropyrimidine is a critical heterocyclic compound widely utilized in the pharmaceutical and fine chemical industries. As a key building block, this pyrimidine derivative serves as an essential intermediate in the synthesis of complex organic molecules, particularly within the realm of medicinal chemistry. Our facility produces this compound under stringent quality management systems to ensure consistency and reliability for downstream applications.

The chemical structure features a pyrimidine ring substituted with an amino group at the second position and a chlorine atom at the fourth position. This specific arrangement provides high reactivity for nucleophilic substitution reactions, making it invaluable for constructing diverse molecular architectures required in modern drug discovery and development processes.

Technical Specifications

We adhere to rigorous analytical standards to guarantee the performance of our chemicals in your synthesis workflows. The following table outlines the typical physical and chemical properties associated with this product batch.

ParameterSpecification
CAS Number3993-78-0
Molecular FormulaC4H4ClN3
Molecular Weight129.548 g/mol
AppearanceOff-white to light brown powder
Assay (Purity)≥98.0%
Moisture Content≤0.5%
Melting Point155-160°C (dec.)
Boiling Point314.6±34.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point144.1±25.7 °C

Industrial Applications

This compound is primarily employed as a strategic intermediate in the manufacturing of active pharmaceutical ingredients (APIs). Notably, it acts as a precursor in the synthesis pathway of antiretroviral medications, contributing to the global supply chain of essential therapies. Beyond pharmaceuticals, it finds utility in agrochemical research and the development of specialized functional materials where heterocyclic chemistry is required.

Chemists value this material for its stability and predictable reactivity profiles during coupling reactions. Whether used in scale-up processes or laboratory research, maintaining high purity levels is crucial to minimizing byproducts and ensuring optimal yield in subsequent synthetic steps.

Quality Assurance and Packaging

Our production process involves multiple purification stages to achieve the specified assay levels. Each batch undergoes comprehensive testing using advanced chromatographic and spectroscopic methods. A Certificate of Analysis (COA) is provided with every shipment to verify compliance with stated specifications.

Standard packaging consists of 25 kg drums, designed to protect the material from moisture and contamination during transit. We also offer customized packaging solutions to meet specific logistical requirements. Proper storage in a cool, ventilated area away from incompatible substances is recommended to maintain product integrity over time.

Why Choose Our Supply

  • Consistent high purity suitable for sensitive synthetic routes.
  • Reliable global supply chain with timely delivery capabilities.
  • Competitive bulk pricing structures for large-scale manufacturers.
  • Technical support available for process optimization inquiries.
  • Compliance with international safety and quality regulations.

Partner with us for your 2-Amino-4-chloropyrimidine requirements. We are committed to supporting your research and production goals with premium chemical solutions and dedicated customer service.