Intermediates

2-Amino-4-fluorobenzoic Acid

  • CAS No.446-32-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Amino-4-fluorobenzoic acid (CAS 446-32-2) designed for advanced organic synthesis and pharmaceutical intermediate applications.

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Product Technical Details

Product Overview

2-Amino-4-fluorobenzoic acid is a highly valued fluorinated aromatic compound widely utilized in the fine chemical and pharmaceutical industries. As a critical building block, this substance serves as a foundational element for constructing complex molecular structures required in modern drug discovery and agrochemical development. Our manufacturing process ensures exceptional consistency and reliability, making it an ideal choice for research laboratories and large-scale production facilities alike.

The introduction of the fluorine atom at the para position significantly enhances the metabolic stability and lipophilicity of downstream products. This specific chemical profile makes it indispensable for medicinal chemists aiming to optimize the pharmacokinetic properties of new therapeutic candidates. We maintain strict control over every batch to guarantee that the material meets rigorous international standards for purity and performance.

Technical Specifications

Quality is paramount in chemical synthesis. Our 2-Amino-4-fluorobenzoic acid undergoes comprehensive analytical testing to verify compliance with specified parameters. The following table outlines the key physical and chemical properties typically observed in our production batches:

ParameterSpecification
CAS Number446-32-2
Molecular FormulaC7H6FNO2
Molecular Weight155.13 g/mol
AppearanceOff-white to brown crystalline powder
Purity (HPLC)≥99.0%
Melting Point192-196°C
Density1.43 g/cm3
Moisture Content≤0.5%

Each certificate of analysis (COA) provides detailed test results, including assay values and impurity profiles, ensuring full transparency for our partners. We consistently achieve assay levels exceeding 99.7%, demonstrating our commitment to superior quality control.

Industrial Applications

This fluorinated benzoic acid derivative is primarily employed as a key intermediate in the synthesis of various pharmaceutical agents. Its unique reactivity allows for versatile functionalization, facilitating the creation of diverse chemical libraries. Common applications include the production of kinase inhibitors, anti-inflammatory drugs, and other specialized therapeutic molecules.

Beyond pharmaceuticals, this compound finds utility in the agrochemical sector, where it contributes to the development of advanced crop protection solutions. The stability provided by the fluorine substituent is particularly beneficial in designing molecules that require enhanced environmental resilience. Researchers also utilize this material in organic synthesis projects focused on creating novel materials and functional polymers.

Quality Assurance and Packaging

We understand that supply chain reliability is crucial for continuous operations. Our facility adheres to strict quality management systems to prevent contamination and ensure product integrity. Every drum is sealed securely to protect against moisture and light exposure during transit.

Standard packaging consists of 25 kg fiber drums, though we offer flexible customization to meet specific logistical requirements. Storage recommendations include keeping the material in a cool, ventilated area away from incompatible substances. Our global logistics network ensures timely delivery, supported by comprehensive technical documentation and regulatory compliance files.