2-Amino-4-(trifluoromethyl)pyridine
- CAS No.106447-97-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Amino-4-(trifluoromethyl)pyridine (CAS 106447-97-6) is a premium pyridine derivative designed for advanced organic synthesis and pharmaceutical intermediate manufacturing.
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Product Overview
2-Amino-4-(trifluoromethyl)pyridine is a highly specialized fluorinated heterocyclic compound that serves as a critical building block in modern organic synthesis. Identified by CAS number 106447-97-6, this chemical features a pyridine ring substituted with an amino group and a trifluoromethyl group, providing unique electronic and steric properties valuable for medicinal chemistry and material science applications. Our facility produces this intermediate under strict quality control standards to ensure consistency and reliability for downstream processes.
The incorporation of the trifluoromethyl moiety significantly enhances the metabolic stability and lipophilicity of final drug candidates, making this compound a preferred choice for pharmaceutical researchers. As a dedicated global manufacturer, we supply this material in bulk quantities to support large-scale production needs while maintaining rigorous purity specifications.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 2-Amino-4-(trifluoromethyl)pyridine |
| CAS Number | 106447-97-6 |
| Molecular Formula | C6H5F3N2 |
| Molecular Weight | 162.113 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity (Assay) | ≥98.0% |
| Melting Point | 70-74 °C |
| Boiling Point | 221.3±40.0 °C at 760 mmHg |
| Density | 1.4±0.1 g/cm3 |
Industrial Applications
This fluorinated pyridine derivative is primarily utilized as a key intermediate in the synthesis of complex pharmaceutical agents. The electron-withdrawing nature of the trifluoromethyl group allows for diverse functionalization reactions, enabling chemists to construct sophisticated molecular architectures. Common applications include the development of kinase inhibitors, anti-inflammatory agents, and other therapeutic compounds where metabolic stability is paramount.
Beyond pharmaceuticals, this compound finds utility in agrochemical research and advanced material science. Its stability under various reaction conditions makes it suitable for cross-coupling reactions, nucleophilic substitutions, and heterocycle formations. Researchers value this building block for its ability to improve the bioavailability and binding affinity of target molecules.
Quality Assurance and Storage
Every batch of 2-Amino-4-(trifluoromethyl)pyridine undergoes comprehensive analytical testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy. We provide a detailed Certificate of Analysis (COA) with each shipment to verify compliance with stated specifications. Our quality management system ensures that industrial purity levels are maintained consistently across all production runs.
To maintain optimal stability, the product should be stored in a cool, ventilated area away from direct sunlight and moisture. Standard packaging involves 25 kg drums, though we offer flexible packaging solutions tailored to specific customer requirements. Proper handling procedures should be followed to ensure safety during transportation and usage in laboratory or industrial settings.
Why Choose Our Supply
As an experienced manufacturer with a robust global supply chain, we commit to delivering high-quality chemical intermediates on schedule. Our technical team provides support for synthesis routes and manufacturing processes, ensuring seamless integration into your production workflow. Contact us today for bulk pricing, custom synthesis options, and detailed technical documentation.
