Intermediates

2-Amino-5-bromo-4-methylpyridine

  • CAS No.98198-48-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Amino-5-bromo-4-methylpyridine (CAS 98198-48-2) designed for advanced organic synthesis. Reliable supply with strict quality control and comprehensive documentation.

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Product Technical Details

Product Overview

2-Amino-5-bromo-4-methylpyridine represents a critical class of halogenated heterocyclic compounds extensively utilized in modern organic synthesis. As a specialized pyridine derivative, this chemical building block features a unique substitution pattern that enhances its reactivity in various coupling reactions. Our manufacturing process ensures consistent quality, making it an ideal candidate for research and development projects requiring high precision. The compound is characterized by its stability and defined physical properties, which facilitate safe handling and storage in industrial laboratory environments.

The molecular structure incorporates a bromine atom at the fifth position and a methyl group at the fourth position of the pyridine ring, alongside an amino group at the second position. This specific arrangement provides versatile sites for further functionalization, allowing chemists to construct complex molecular architectures efficiently. Whether used in the development of novel agrochemicals or pharmaceutical intermediates, the reliability of the raw material is paramount to the success of the downstream synthesis.

Technical Specifications

We adhere to rigorous quality control standards to guarantee that every batch meets or exceeds industry expectations. The following table outlines the key physical and chemical parameters associated with this product. Our internal testing protocols verify identity, purity, and moisture content to ensure compatibility with sensitive reaction conditions.

ParameterSpecification
CAS Number98198-48-2
Molecular FormulaC6H7BrN2
Molecular Weight187.037 g/mol
AppearanceWhite to light yellow crystalline powder
Assay (Purity)≥98.0%
Moisture Content≤0.5%
Melting Point148-151 °C
Boiling Point254.2±35.0 °C at 760 mmHg
Density1.6±0.1 g/cm3

Industrial Applications

This brominated pyridine derivative serves as a fundamental intermediate in the production of fine chemicals. Its primary utility lies in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, where the bromine atom acts as a leaving group for carbon-carbon or carbon-heteroatom bond formation. The presence of the amino group also allows for derivatization through acylation or alkylation, expanding the scope of possible synthetic routes.

Industries relying on advanced organic synthesis value this material for its consistent performance and high purity profile. It is commonly employed in the preparation of specialized ligands, catalysts, and bioactive molecule precursors. By sourcing from a verified global manufacturer, clients can mitigate supply chain risks and ensure continuity in their production schedules. The material is suitable for scale-up processes where reproducibility is essential.

Quality Assurance and Packaging

Quality assurance is integral to our operation. Each production lot undergoes comprehensive analysis, including HPLC and NMR spectroscopy, to confirm structural integrity and purity levels. A Certificate of Analysis (COA) is provided with every shipment, detailing the test results against our factory standards. This transparency allows customers to validate the material before integrating it into their workflows.

Standard packaging consists of 25 kg drums, designed to protect the contents from moisture and physical damage during transit. Custom packaging solutions are available upon request to accommodate specific logistical requirements. Proper storage involves keeping the containers in a cool, ventilated area away from direct sunlight and incompatible substances. Adhering to these storage guidelines ensures the long-term stability of the chemical properties.