Intermediates

2-Amino-5-diethylaminopentane

  • CAS No.140-80-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Amino-5-diethylaminopentane (CAS 140-80-7), a key pharmaceutical intermediate used in the synthesis of antimalarial agents and other complex APIs.

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Product Technical Details

Product Overview

2-Amino-5-diethylaminopentane (CAS 140-80-7) is a high-value aliphatic diamine widely employed as a critical building block in pharmaceutical synthesis. This compound serves as an essential intermediate in the production of chloroquine diphosphate and related therapeutic molecules, demonstrating its strategic importance in medicinal chemistry workflows.

Specifications

Molecular FormulaC9H22N2
Molecular Weight158.284 g/mol
AppearanceColorless transparent liquid
Assay≥99.0%
Density0.8 ± 0.1 g/cm³
Boiling Point200.5 ± 8.0 °C at 760 mmHg
Flash Point68.3 ± 0.0 °C
Vapour Pressure0.3 ± 0.4 mmHg at 25 °C
Refractive Index1.453

Industrial Applications

As a versatile diamine scaffold, 2-Amino-5-diethylaminopentane is primarily utilized in the multi-step synthesis of antimalarial pharmaceuticals, particularly chloroquine diphosphate (CAS 50-63-5). Its dual amine functionality enables selective derivatization, making it ideal for constructing complex nitrogen-containing heterocycles found in advanced organic synthesis and neurological therapeutics research.

  • Serves as a core intermediate in regulated API manufacturing pathways
  • Enables efficient chain elongation and functional group manipulation
  • Compatible with standard amine protection and coupling chemistries

For industrial-scale procurement, the product is typically supplied in 200 kg drums, with custom packaging available upon request. Storage should be in a cool, well-ventilated area away from oxidizing agents and sources of ignition due to its moderate flash point.