2-Amino-5-fluoro-N-phenylbenzamide
- CAS No.60041-89-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Amino-5-fluoro-N-phenylbenzamide (CAS 60041-89-6) designed for pharmaceutical synthesis. Ideal intermediate for Idelalisib production with ≥98.0% assay guarantee.
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Product Overview
2-Amino-5-fluoro-N-phenylbenzamide is a specialized fluorinated benzamide derivative serving as a critical building block in modern medicinal chemistry. As a key pharmaceutical intermediate, this compound is extensively utilized in the synthesis of kinase inhibitors, particularly for the production of Idelalisib. The introduction of the fluorine atom at the fifth position enhances metabolic stability and bioavailability in downstream active pharmaceutical ingredients (APIs). Our manufacturing facility ensures consistent quality through rigorous process controls, making this material a reliable choice for large-scale drug development projects.
We understand the stringent requirements of the pharmaceutical industry. Therefore, every batch undergoes comprehensive analytical testing to confirm structural integrity and purity levels. This compound is supplied as a white crystalline powder, optimized for solubility and reactivity in subsequent coupling reactions. Our commitment to excellence supports researchers and production teams in achieving efficient synthesis routes while maintaining compliance with international regulatory standards.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 60041-89-6 |
| Molecular Formula | C13H11FN2O |
| Molecular Weight | 230.24 g/mol |
| Appearance | White powder |
| Assay (Purity) | ≥98.0% |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 322.9±32.0 °C at 760 mmHg |
| Flash Point | 149.1±25.1 °C |
Industrial Applications
The primary application of 2-Amino-5-fluoro-N-phenylbenzamide lies in the manufacturing of targeted cancer therapies. It acts as a crucial precursor in the construction of the PI3K delta inhibitor framework found in Idelalisib. The chemical structure allows for specific functionalization, enabling chemists to build complex heterocyclic systems with high precision. Beyond oncology, fluorinated benzamides are increasingly explored in anti-inflammatory and immunomodulatory research due to their favorable pharmacokinetic profiles.
Our clients leverage this intermediate for both process development and commercial-scale production. The high purity level minimizes impurity carryover into the final API, simplifying purification steps and reducing overall production costs. We provide technical support to assist with scale-up challenges, ensuring a smooth transition from laboratory synthesis to industrial manufacturing.
Quality Assurance and Packaging
Quality is the cornerstone of our supply chain. Each production lot is accompanied by a Certificate of Analysis (COA) detailing test results against established specifications. We employ advanced chromatography and spectroscopy methods to verify identity and content. Storage recommendations include keeping the material in a cool, ventilated environment away from direct sunlight and moisture to maintain stability over extended periods.
- Standard packaging includes 25 kg drums lined with polyethylene bags.
- Custom packaging solutions are available upon request to suit specific logistical needs.
- Global shipping capabilities ensure timely delivery to major pharmaceutical hubs.
- Strict confidentiality agreements protect client intellectual property and project details.
Partnering with us means accessing a stable supply of high-performance chemical intermediates. We invite inquiries regarding bulk pricing, sample availability, and custom synthesis requirements for your specific project needs.
