Intermediates

2-Amino-5-fluorobenzonitrile

  • CAS No.61272-77-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Amino-5-fluorobenzonitrile serves as a critical fluorinated building block for advanced organic synthesis and pharmaceutical intermediate manufacturing.

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Product Technical Details

Product Overview

2-Amino-5-fluorobenzonitrile is a specialized fluorinated aromatic compound designed for use in complex organic synthesis pathways. As a key building block in modern medicinal chemistry, this nitrile derivative offers exceptional reactivity and stability, making it an indispensable resource for research and industrial production. Our manufacturing process ensures consistent quality, adhering to strict international standards for chemical intermediates.

The introduction of fluorine atoms into organic molecules often enhances metabolic stability and bioavailability in pharmaceutical candidates. Consequently, this compound is highly valued by process chemists developing new therapeutic agents. We supply this material with a focus on purity and reliability, supporting both small-scale laboratory research and large-scale commercial manufacturing needs.

Technical Specifications

Quality control is paramount in the production of fine chemical intermediates. Each batch undergoes rigorous analytical testing to verify identity and purity levels. The following table outlines the standard physical and chemical properties associated with this product.

ParameterSpecification
Chemical Name2-Amino-5-fluorobenzonitrile
CAS Number61272-77-3
Molecular FormulaC7H5FN2
Molecular Weight136.126 g/mol
AppearanceOff-white to grey crystalline powder
Assay (Purity)≥98.0%
Melting Point92-96°C (lit.)
Boiling Point275.5±25.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point120.4±23.2 °C

Industrial Applications

This fluorinated nitrile serves as a versatile precursor in the synthesis of various heterocyclic compounds. Its primary utility lies in the construction of more complex molecular architectures required for pharmaceutical development. Common applications include serving as a starting material for kinase inhibitors, receptor modulators, and other bioactive small molecules.

  • Pharmaceutical Intermediate: Used in the multi-step synthesis of active pharmaceutical ingredients (APIs).
  • Agrochemical Development: Employed in the creation of novel pesticide and herbicide structures.
  • Material Science: Utilized in the development of specialized polymers and functional materials.
  • Research Reagent: Essential for academic and industrial laboratories focusing on fluoro-organic chemistry.

Storage and Handling

To maintain product integrity, proper storage conditions must be observed. The material should be kept in a cool, ventilated area away from direct sunlight and moisture sources. Containers must remain tightly sealed when not in use to prevent contamination or degradation. Standard laboratory safety protocols apply during handling, including the use of appropriate personal protective equipment.

Supply and Packaging

We offer flexible packaging solutions to meet diverse client requirements. Standard shipments are packaged in 25 kg drums, ensuring safe transport and ease of handling. For larger volume requirements or specific containment needs, custom packaging options are available upon request. Our global logistics network ensures timely delivery, supported by comprehensive documentation including Certificates of Analysis (COA) for every batch.