Intermediates

2-Amino-5-fluoropyridine

  • CAS No.21717-96-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Amino-5-fluoropyridine (CAS 21717-96-4) is an essential heterocyclic building block for pharmaceutical synthesis, available in bulk with certified quality.

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Product Technical Details

Product Overview

2-Amino-5-fluoropyridine represents a critical class of fluorinated heterocyclic compounds widely utilized in modern organic synthesis and medicinal chemistry. As a key pharmaceutical intermediate, this substance serves as a fundamental building block for the development of various therapeutic agents. Our manufacturing process ensures exceptional consistency and reliability, making it an ideal choice for research laboratories and large-scale production facilities alike. The introduction of the fluoro substituent at the fifth position of the pyridine ring significantly enhances the metabolic stability and bioavailability of downstream drug candidates.

We are committed to supplying high-quality chemical materials that meet stringent international standards. Each batch undergoes rigorous quality control testing to verify identity, purity, and physical properties. This dedication to excellence allows our partners to accelerate their drug discovery pipelines with confidence. Whether used in kinase inhibitor synthesis or novel agrochemical development, this intermediate provides the necessary structural foundation for complex molecular architectures.

Key Specifications

Our production facility employs advanced purification techniques to achieve superior purity levels. The physical characteristics of this compound are well-defined, ensuring predictable performance during chemical reactions. Proper handling and storage are essential to maintain the integrity of the material over time. We recommend keeping the product in a tightly sealed container away from moisture and direct sunlight to prevent degradation. The following table outlines the typical analytical data associated with our standard production batches.

Items of AnalysisStandard of AnalysisTest Results
AppearanceWhite to light yellow solidConform
Assay (HPLC)≥95.0%98.54%
Moisture≤0.5%0.12%
Melting point93-99℃95-97℃
ConclusionConforms to Factory Standard

Industrial Applications

This fluorinated pyridine derivative finds extensive application in the synthesis of active pharmaceutical ingredients (APIs). Its unique electronic properties facilitate various coupling reactions, including nucleophilic aromatic substitution and cross-coupling protocols. Chemists value this intermediate for its versatility in constructing diverse heterocyclic systems. Beyond pharmaceuticals, it is also explored in the development of advanced materials and specialty chemicals where fluorine incorporation is desired for performance enhancement.

Our global supply chain ensures timely delivery to customers worldwide. We understand the critical nature of supply continuity in manufacturing environments. Therefore, we maintain substantial inventory levels to accommodate both urgent research needs and scheduled production runs. Our technical support team is available to provide documentation such as Certificates of Analysis (COA) and Material Safety Data Sheets (MSDS) upon request.

Quality Assurance and Safety

Safety is paramount in the handling of all chemical substances. While this intermediate is stable under recommended conditions, standard laboratory safety protocols should always be observed. Personnel should wear appropriate personal protective equipment during handling. Our quality assurance system tracks every step from raw material sourcing to final packaging. This traceability guarantees that every drum or bag delivered meets the specified criteria for purity and composition. Partner with us for reliable sourcing of premium chemical intermediates.