Intermediates

2-Amino-5-methylpyridine

  • CAS No.1603-41-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Amino-5-methylpyridine (CAS 1603-41-4), a key agrochemical intermediate used in the synthesis of acetamiprid and other nitrogen-containing heterocyclic compounds.

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Product Technical Details

Product Overview

2-Amino-5-methylpyridine is a high-value heterocyclic organic compound widely employed as a critical building block in the agrochemical and pharmaceutical industries. With a molecular formula of C6H8N2 and a molecular weight of 108.14 g/mol, this compound features a pyridine ring substituted with both an amino group at the 2-position and a methyl group at the 5-position, conferring unique reactivity for nucleophilic substitution and condensation reactions.

Specifications

Molecular FormulaC6H8N2
Molecular Weight108.141 g/mol
CAS Number1603-41-4
AppearanceWhite to yellowish crystalline powder
Assay (GC)≥99.0%
Moisture (KF)≤0.5%
Melting Point75–81 °C
Density1.1 ± 0.1 g/cm³
Boiling Point227.0 ± 0.0 °C at 760 mmHg
Flash Point110.9 ± 9.0 °C

Industrial Applications

This compound serves primarily as a synthetic intermediate in the production of neonicotinoid insecticides, notably acetamiprid (CAS 135410-20-7). Its structural motif enables efficient construction of complex bioactive molecules through well-established cross-coupling and cyclization protocols. Additional applications include:

  • Intermediate in the synthesis of veterinary and crop protection agents
  • Precursor for functionalized pyridine derivatives in medicinal chemistry
  • Building block for ligands in catalytic systems

Stored in a cool, dry, and well-ventilated area away from oxidizing agents, 2-Amino-5-methylpyridine is typically packed in 25 kg fiber drums or customized packaging per client specifications. As a non-controlled, non-hazardous intermediate under standard regulatory frameworks, it supports scalable and compliant manufacturing workflows across global supply chains.