Intermediates

2-Amino-5-nitro-4-picoline

  • CAS No.21901-40-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Amino-5-nitro-4-picoline (CAS 21901-40-6) designed for advanced organic synthesis. Reliable supply with strict quality control.

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Product Technical Details

Product Overview

2-Amino-5-nitro-4-picoline represents a critical component within the realm of heterocyclic chemistry, serving as a versatile building block for complex organic synthesis. This pyridine derivative is meticulously manufactured to meet the rigorous demands of modern pharmaceutical and agrochemical research. Our facility ensures that every batch undergoes stringent quality control protocols to guarantee consistency and reliability for downstream applications. The strategic positioning of the amino and nitro groups on the picoline scaffold provides unique reactivity profiles that are highly sought after in medicinal chemistry.

As a specialized intermediate, this compound facilitates the construction of more elaborate molecular structures. Its unique substitution pattern on the pyridine ring allows for diverse chemical transformations, making it an invaluable asset for chemists developing new active pharmaceutical ingredients or advanced functional materials. We are committed to supplying this material with the highest standards of purity and documentation. Our production capabilities are scaled to accommodate both pilot-scale research requirements and large-scale commercial manufacturing needs.

Technical Specifications

ParameterValue
CAS Number21901-40-6
Molecular FormulaC6H7N3O2
Molecular Weight153.14 g/mol
Purity (HPLC)≥99.0%
AppearanceOrange to yellow-brown powder

Physical and Chemical Properties

The physical characteristics of 2-Amino-5-nitro-4-picoline are well-defined to assist in process optimization. The compound exhibits a melting point range between 223 and 225 degrees Celsius, indicating high thermal stability suitable for various reaction conditions. With a density of approximately 1.354 g/cm3, it integrates effectively into standard laboratory and industrial workflows. The boiling point is recorded at 351.9 degrees Celsius, and the flash point is established at 166.6 degrees Celsius, necessitating appropriate safety measures during handling and storage.

Industrial Applications

  • Pharmaceutical Intermediate: Utilized in the synthesis of novel drug candidates targeting various therapeutic areas including oncology and infectious diseases.
  • Agrochemical Development: Serves as a crucial precursor for creating advanced pesticides and herbicides with improved environmental profiles.
  • Fine Chemical Synthesis: Employed in the production of specialized dyes, pigments, and functional electronic materials.
  • Research and Development: Essential for academic and industrial labs focusing on heterocyclic chemistry and method development.
  • Custom Synthesis: Available for bespoke chemical projects requiring specific purity grades or isotopic labeling.

Quality Assurance and Logistics

We prioritize product integrity from synthesis to delivery. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) verifying all specification parameters including purity, moisture content, and identity. The material is packaged in 25 kg drums to ensure protection during transit, though custom packaging solutions are available upon request to suit specific logistical constraints. Proper storage in a cool, ventilated environment is recommended to maintain long-term stability. Our global logistics network ensures timely delivery to support your production schedules without interruption. Safety data sheets (SDS) are provided with every order to ensure compliant handling.