Intermediates

2-Amino-6-chloropurine-9-riboside

  • CAS No.2004-07-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate used in nucleoside analog synthesis. Available in bulk with full quality documentation.

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Product Technical Details

Product Overview

2-Amino-6-chloropurine-9-riboside is a specialized nucleoside analog intermediate characterized by its high chemical stability and reactivity profile. This compound serves as a critical building block in the medicinal chemistry sector, particularly for the development of advanced therapeutic agents. Our manufacturing process ensures exceptional purity levels, making it an ideal candidate for complex organic synthesis workflows where consistency and reliability are paramount.

As a chlorinated purine riboside derivative, this material features a specific substitution pattern that facilitates further functionalization. The presence of the chloro group at the six-position allows for versatile nucleophilic substitution reactions, enabling chemists to introduce various functional groups required for final active pharmaceutical ingredient (API) structures. We adhere to strict production protocols to maintain the integrity of the glycosidic bond and prevent degradation during synthesis and storage.

Technical Specifications

Quality control is integral to our supply chain. Each batch undergoes rigorous analytical testing to confirm compliance with international standards. The following table outlines the key physical and chemical parameters guaranteed for this product:

ParameterSpecification
CAS Number2004-07-1
Molecular FormulaC10H12ClN5O4
Molecular Weight301.69 g/mol
AppearanceWhite or off-white crystalline powder
Assay (HPLC)≥99.0%
Loss on Drying≤2.0%
Residue on Ignition≤0.1%
Heavy Metals≤10 ppm
Melting Point165-167°C

Industrial Applications

This intermediate is primarily utilized in the pharmaceutical industry for the synthesis of nucleoside-based therapeutics. It plays a vital role in the research and development of antiviral and oncology treatments. Due to its structural similarity to natural nucleosides, it can be incorporated into synthetic pathways designed to mimic biological processes, thereby inhibiting specific enzymatic activities in target pathogens or malignant cells.

Researchers value this compound for its compatibility with various protection and deprotection strategies common in carbohydrate chemistry. Whether used in academic research or large-scale industrial manufacturing, the material provides a reliable foundation for constructing complex molecular architectures. Our team supports clients with technical data packages that assist in process optimization and regulatory filings.

Quality Assurance and Storage

We maintain a robust quality management system to ensure product consistency. Every shipment is accompanied by a Certificate of Analysis (COA) detailing batch-specific test results. To preserve stability, the product should be stored in a cool, ventilated environment away from direct sunlight and moisture. Proper handling procedures are recommended to maintain the specified purity levels throughout the product lifecycle.

Packaging options include standard 25 kg drums, with customization available to meet specific logistical requirements. Our global distribution network ensures timely delivery while maintaining cold chain or protective conditions as necessary. For bulk inquiries or custom synthesis requests, our technical sales team is available to provide detailed quotations and supply chain solutions tailored to your project needs.