2-Amino-6-fluorobenzoic acid
- CAS No.434-76-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Amino-6-fluorobenzoic acid (CAS 434-76-4) designed for advanced organic synthesis and pharmaceutical intermediate applications. Available in bulk quantities with certified quality assurance.
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Product Overview
2-Amino-6-fluorobenzoic acid is a specialized fluorinated aromatic compound serving as a critical building block in modern medicinal chemistry and agrochemical development. Characterized by the strategic placement of both amino and fluoro substituents on the benzoic acid backbone, this molecule offers unique reactivity profiles essential for constructing complex heterocyclic systems. Our manufacturing process ensures exceptional batch-to-batch consistency, making it an ideal choice for research laboratories and large-scale production facilities alike.
The introduction of fluorine atoms into organic molecules is a cornerstone strategy in drug design, often enhancing metabolic stability, lipophilicity, and bioavailability. As a key precursor, this compound facilitates the synthesis of various quinolone antibiotics, kinase inhibitors, and other high-value therapeutic agents. We adhere to strict quality management systems to deliver material that meets the rigorous demands of global pharmaceutical supply chains.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 2-Amino-6-fluorobenzoic acid |
| CAS Registry Number | 434-76-4 |
| Molecular Formula | C7H6FNO2 |
| Molecular Weight | 155.13 g/mol |
| Appearance | Off-white to white powder |
| Purity (HPLC) | ≥99.0% |
| Melting Point | 167-169°C |
| Density | 1.43 g/cm³ |
| Refractive Index | 1.606 |
Industrial Applications
This fluorinated intermediate is predominantly utilized in the multi-step synthesis of active pharmaceutical ingredients (APIs). The ortho-amino and meta-fluoro arrangement allows for diverse cyclization reactions, including the formation of benzimidazoles and quinolines. Beyond human health applications, it serves as a vital component in the development of advanced crop protection agents, where fluorine substitution improves environmental persistence and biological activity.
Chemists value this reagent for its compatibility with various coupling reactions and its stability under standard storage conditions. Whether used in process research and development or scaled-up manufacturing, our product provides a reliable foundation for creating next-generation chemical entities. We support clients with technical data packages to streamline regulatory filings and process validation.
Quality Assurance and Safety
Every production lot undergoes comprehensive analytical testing, including HPLC, GC-MS, and NMR spectroscopy, to verify identity and purity. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with international standards. Our facility operates under strict environmental and safety protocols to minimize risk and ensure product integrity.
- Packaged in 25 kg drums or customized containers based on client logistics.
- Stored in a cool, dry, and well-ventilated area away from incompatible substances.
- Global shipping capabilities with secure handling procedures for fine chemicals.
- Dedicated technical support for synthesis optimization and scale-up queries.
Choose our company as your trusted partner for high-performance chemical intermediates. We combine decades of synthesis expertise with a commitment to customer success, delivering materials that empower innovation in the life sciences sector.
