2-Amino-6-fluorobenzonitrile
- CAS No.77326-36-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Amino-6-fluorobenzonitrile (CAS 77326-36-4) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for pharmaceutical and agrochemical intermediates.
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Product Overview
2-Amino-6-fluorobenzonitrile is a highly specialized fluorinated aromatic compound that serves as a critical building block in modern organic synthesis. Characterized by the presence of both an amino group and a nitrile moiety on a fluorinated benzene ring, this chemical exhibits unique reactivity profiles that make it indispensable for the development of complex pharmaceutical agents and agrochemical formulations. Our manufacturing process ensures exceptional consistency and purity, meeting the rigorous demands of research and industrial production environments.
As a key intermediate, this compound facilitates the introduction of fluorine atoms into molecular structures, a strategy often employed to enhance metabolic stability and bioavailability in drug candidates. The strategic positioning of the functional groups allows for versatile synthetic transformations, including nucleophilic substitutions and cyclization reactions. We prioritize quality control at every stage of production to deliver a product that supports efficient downstream processing.
Key Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 2-Amino-6-fluorobenzonitrile |
| CAS Number | 77326-36-4 |
| Molecular Formula | C7H5FN2 |
| Molecular Weight | 136.126 g/mol |
| Appearance | White to off-white powder |
| Assay (Purity) | ≥98.0% |
| Melting Point | 125-128 °C |
| Boiling Point | 275.8±25.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 120.6±23.2 °C |
Industrial Applications
This fluorinated nitrile derivative is extensively utilized in the pharmaceutical industry for the synthesis of kinase inhibitors and other therapeutic molecules where fluorine substitution is crucial for optimizing pharmacokinetic properties. Additionally, it finds application in the agrochemical sector for developing novel pesticides and herbicides with improved environmental profiles. Material science researchers also leverage this compound for creating advanced polymers and functional materials with specific electronic or thermal characteristics.
The versatility of 2-Amino-6-fluorobenzonitrile allows chemists to explore diverse synthetic routes. The nitrile group can be hydrolyzed to carboxylic acids or reduced to amines, while the amino group can participate in acylation or alkylation reactions. The fluorine atom provides a handle for further functionalization or serves as a bioisostere in medicinal chemistry designs. Our team supports clients with technical data to facilitate these complex transformations.
Quality Assurance and Handling
We adhere to strict quality management systems to ensure that every batch of 2-Amino-6-fluorobenzonitrile meets specified purity standards. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing physical and chemical properties. Proper storage is essential to maintain product integrity. The material should be kept in a cool, ventilated area away from direct sunlight and incompatible substances.
- Consistent high purity levels for reliable reaction outcomes
- Robust packaging solutions to prevent contamination during transit
- Technical support available for synthesis optimization
- Flexible packaging options including 25 kg drums or custom requirements
- Global logistics capabilities for timely delivery
Partnering with us ensures access to a stable supply chain for this vital chemical intermediate. We are committed to supporting innovation in pharmaceutical and chemical industries through the provision of high-quality raw materials and dedicated customer service.
