Intermediates

2-Anilinoethanol

  • CAS No.122-98-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Anilinoethanol (CAS 122-98-5) designed for pharmaceutical synthesis, specifically as a key intermediate for anticoagulant medications like Rivaroxaban.

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Product Technical Details

Product Overview

2-Anilinoethanol, also known commercially as N-(2-Hydroxyethyl)aniline, is a critical organic compound utilized extensively within the fine chemical and pharmaceutical industries. As a specialized amino alcohol derivative, this substance serves as a fundamental building block in the synthesis of complex therapeutic agents. Our facility produces this intermediate under strict quality control protocols to ensure consistent molecular integrity and high purity levels suitable for demanding downstream applications.

The chemical structure combines an aniline moiety with a hydroxyethyl group, providing unique reactivity profiles that are essential for multi-step organic synthesis pathways. We understand the importance of reliability in the supply chain for pharmaceutical manufacturing, which is why our production processes are optimized for scalability and batch-to-batch consistency.

Key Specifications and Physical Properties

Quality assurance is paramount in the production of pharmaceutical intermediates. Our 2-Anilinoethanol undergoes rigorous analytical testing using gas chromatography and other advanced methods to verify compliance with international standards. The following table outlines the typical physical properties and quality specifications associated with our premium grade product.

ParameterSpecification
CAS Number122-98-5
Molecular FormulaC8H11NO
Molecular Weight137.179 g/mol
AppearanceColorless to light yellow liquid
Assay (GC)≥99.0%
Density1.1±0.1 g/cm3
Boiling Point286.9±13.0 °C at 760 mmHg
Flash Point151.4±10.5 °C
Free Aniline Content≤0.4%

Industrial Applications

The primary application of 2-Anilinoethanol lies in the pharmaceutical sector, where it acts as a vital precursor in the manufacturing of anticoagulant medications. Specifically, it is recognized as a key intermediate in the synthesis route for Rivaroxaban, a widely prescribed therapeutic agent. The high purity of our product ensures that downstream reactions proceed efficiently, minimizing impurity carryover and maximizing final drug yield.

Beyond pharmaceuticals, this compound may be utilized in the development of specialized organic materials and agrochemical formulations where amino alcohol functionality is required. Our technical team supports clients in optimizing their synthesis routes to leverage the full potential of this chemical building block.

Quality Assurance and Safety

We adhere to stringent safety and quality management systems. Every batch is accompanied by a Certificate of Analysis (COA) detailing test results against our factory standards. Impurity profiles, including residual aniline and dihydroxyethyl aniline, are closely monitored to ensure they remain well within safe limits. This commitment to quality reduces risk for our partners during their regulatory filings and production processes.

Packaging and Storage

To maintain product stability during transit and storage, 2-Anilinoethanol is packaged in secure 200 kg drums. Custom packaging solutions are available upon request to meet specific logistical requirements. The product should be stored in a cool, ventilated area away from direct sunlight and incompatible materials. Proper handling procedures should be followed in accordance with standard chemical safety guidelines to ensure workplace safety.