Intermediates

2-Benzyl-1H-benzimidazole

  • CAS No.621-72-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Benzyl-1H-benzimidazole (CAS 621-72-7) designed for pharmaceutical synthesis. Reliable supply for hypertension drug intermediates with strict quality control.

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Product Technical Details

Product Overview

2-Benzyl-1H-benzimidazole is a highly valued organic compound widely utilized within the pharmaceutical and chemical industries. Identified by the CAS registry number 621-72-7, this benzimidazole derivative serves as a critical building block in the synthesis of various active pharmaceutical ingredients (APIs). Our facility specializes in the production of this intermediate with a commitment to exceeding industry standards for purity and consistency. The compound features a stable benzimidazole core substituted with a benzyl group, providing unique reactivity profiles suitable for complex medicinal chemistry applications.

We understand the stringent requirements of modern drug development. Therefore, our manufacturing processes are designed to ensure minimal impurity levels and batch-to-batch reproducibility. Whether utilized for research and development or large-scale commercial production, this material provides a reliable foundation for synthesizing therapeutic agents, particularly those targeting cardiovascular conditions.

Chemical Properties

The physical and chemical characteristics of 2-Benzyl-1H-benzimidazole make it suitable for various synthetic routes. Below are the key technical parameters that define the quality of our substance. These properties are verified through advanced analytical methods including HPLC, NMR, and mass spectrometry.

PropertyValue
Chemical Name2-Benzyl-1H-benzimidazole
CAS Number621-72-7
Molecular FormulaC14H12N2
Molecular Weight208.26 g/mol
Melting Point187°C
Boiling Point453.5°C at 760 mmHg
Density1.193 g/cm3
Refractive Index1.680

Quality Specifications

Quality assurance is the cornerstone of our supply chain. Each batch undergoes rigorous testing to confirm compliance with specified parameters. We maintain a purity level exceeding 99 percent, ensuring that downstream synthesis processes are not compromised by contaminants. Our quality control team monitors critical factors such as loss on drying and sulphated ash to guarantee material integrity.

Specification ItemStandard
AppearanceWhite or yellow white microfine powder
Purity (HPLC)Greater than 99 percent
Loss on DryingNMT 1.00 percent
Sulphated AshNMT 0.20 percent
Assay (Anhydrous)97.0 percent to 102.0 percent
SolubilitySubstances soluble in light petroleum NMT 0.20 percent

Industrial Applications

This benzimidazole derivative is primarily employed as a pharmaceutical intermediate. It plays a significant role in the manufacturing pipeline for medications used in the management of hypertension and other cardiovascular disorders. The chemical structure allows for further functionalization, making it a versatile precursor in organic synthesis. Additionally, it is utilized in academic research for exploring new biological activities associated with the benzimidazole scaffold.

Storage and Handling

To maintain optimal stability and performance, proper storage conditions are essential. The material should be kept in a well-closed container at low temperatures, ideally around 4 degrees Celsius. It is crucial to protect the substance from moisture, excessive heat, and direct light exposure. Adhering to these storage guidelines ensures that the chemical properties remain unchanged over time. Always handle with appropriate personal protective equipment in a well-ventilated area.

Why Choose Our Supply

  • Consistent high purity levels suitable for sensitive synthetic processes.
  • Comprehensive documentation including Certificate of Analysis (COA) for every batch.
  • Flexible packaging options including 25kg cardboard drums or custom requirements.
  • Global logistics capabilities ensuring timely delivery to your facility.
  • Dedicated technical support for synthesis route optimization and troubleshooting.

We are committed to being your trusted partner in chemical sourcing. Contact our sales team today to discuss your specific volume requirements and receive a competitive bulk price quote.