Intermediates

2-Bromo-1,1,1-trifluoroethane

  • CAS No.421-06-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Bromo-1,1,1-trifluoroethane serves as a critical fluorinated building block for advanced pharmaceutical and material synthesis.

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Product Technical Details

Product Overview

2-Bromo-1,1,1-trifluoroethane is a highly specialized fluorinated organic compound that plays a pivotal role in modern chemical synthesis. As a versatile halogenated intermediate, it introduces the trifluoroethyl group into complex molecular structures, enhancing metabolic stability and lipophilicity in target molecules. Our facility ensures rigorous production standards to deliver this reagent with exceptional purity, suitable for demanding research and industrial applications.

This compound is characterized by its unique physicochemical properties, including a low boiling point and high density, which facilitate specific reaction conditions in organic synthesis. The presence of the bromine atom acts as an excellent leaving group, enabling efficient nucleophilic substitution reactions. This makes it an indispensable tool for medicinal chemists and material scientists aiming to develop next-generation compounds with improved performance profiles.

Technical Specifications

ParameterValue
CAS Number421-06-7
Molecular FormulaC2H2BrF3
Molecular Weight162.94 g/mol
AppearanceColorless liquid
Density1.788 g/cm3
Boiling Point26°C
Melting Point-94°C
Refractive Index1.333
Vapor Pressure772 mmHg at 25°C

Industrial Applications

The utility of 2-Bromo-1,1,1-trifluoroethane spans across multiple high-value sectors. In the pharmaceutical industry, it is extensively used as a key building block for synthesizing active pharmaceutical ingredients (APIs). The trifluoroethyl moiety is known to improve the bioavailability and binding affinity of drug candidates, making this intermediate crucial for oncology, neurology, and infectious disease research.

Beyond pharmaceuticals, this chemical is vital in the development of new materials and agrochemicals. It serves as a precursor for fluorinated polymers and specialty gases used in electronic manufacturing. In agriculture, it contributes to the formulation of novel pesticides with enhanced environmental profiles. Our commitment to a complete fluorochemical platform ensures that customers receive consistent quality tailored to these diverse application needs.

Quality Assurance and Supply

We maintain a comprehensive quality control system that covers every stage from raw material procurement to final product storage. Each batch undergoes strict analytical testing to verify identity, purity, and physical constants. Certificates of Analysis (COA) are provided with every shipment to guarantee compliance with international standards. Our logistics network supports global delivery, ensuring secure packaging and timely arrival for bulk orders.

Safety and storage are paramount in handling fluorinated intermediates. We recommend storing this product in a cool, dry, and well-ventilated area away from incompatible substances. Proper handling procedures should be followed to maintain integrity and safety during laboratory or plant operations. Partner with us for reliable supply chain solutions and technical support in fluorine chemistry.