Intermediates

2-Bromo-1-chloro-4-fluorobenzene

  • CAS No.201849-15-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity halogenated benzene derivative designed for pharmaceutical synthesis. Reliable supply with comprehensive quality documentation.

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Product Technical Details

Product Overview

2-Bromo-1-chloro-4-fluorobenzene is a specialized halogenated aromatic compound that serves as a critical building block in modern organic synthesis. Characterized by its unique substitution pattern involving bromine, chlorine, and fluorine atoms on the benzene ring, this chemical intermediate offers exceptional reactivity for various cross-coupling reactions. Our manufacturing process ensures consistent quality and high purity levels, making it an ideal choice for research and development teams working on complex pharmaceutical agents and advanced agrochemical formulations.

As a leading global manufacturer, we understand the stringent requirements of the fine chemical industry. This product is synthesized under strictly controlled conditions to minimize impurities and maximize yield. The presence of multiple halogen substituents provides versatile sites for further functionalization, allowing chemists to construct sophisticated molecular architectures efficiently. Whether utilized in nucleophilic aromatic substitution or metal-catalyzed coupling processes, this compound delivers reliable performance.

Key Specifications

Parameter Value
CAS Number 201849-15-2
Molecular Formula C6H3BrClF
Molecular Weight 209.44 g/mol
Purity ≥99.0%
Appearance Clear colourless to light yellow liquid
Boiling Point 202.1°C at 760 mmHg
Density 1.75 g/cm3
Flash Point 76°C
Refractive Index 1.545

Industrial Applications

This halogenated benzene derivative is primarily employed as a key intermediate in the pharmaceutical industry. It facilitates the synthesis of active pharmaceutical ingredients (APIs) where specific halogen positioning is crucial for biological activity. The fluorine atom enhances metabolic stability, while the bromine and chlorine groups offer handles for subsequent chemical transformations. Common applications include the development of neurological therapeutics, oncology drugs, and cardiovascular medications.

  • Pharmaceutical intermediate synthesis
  • Agrochemical product development
  • Advanced organic synthesis research
  • Custom chemical manufacturing projects

Quality Assurance and Safety

Quality is paramount in our production facility. Every batch of 2-Bromo-1-chloro-4-fluorobenzene undergoes rigorous testing using advanced analytical techniques such as Gas Chromatography (GC) and High-Performance Liquid Chromatography (HPLC). We provide a comprehensive Certificate of Analysis (COA) with each shipment to verify compliance with specified parameters. Our commitment to safety extends to packaging and logistics, ensuring that the product arrives in optimal condition.

For storage, this chemical should be kept in a tightly closed container within a cool, dry, and well-ventilated area. It is essential to keep the material away from incompatible substances such as strong oxidizing agents. Proper handling procedures, including the use of personal protective equipment, are recommended during laboratory or industrial use. Our technical support team is available to assist with safety data sheets (SDS) and specific handling guidelines tailored to your operational needs.

Supply Chain Reliability

We offer competitive bulk pricing and flexible packaging options, including 25kg drums, to accommodate various scale requirements. Our global logistics network ensures timely delivery to laboratories and manufacturing plants worldwide. By choosing our company as your partner, you gain access to a stable supply chain, consistent product quality, and expert technical support for your synthesis projects.