Intermediates

2-Bromo-1-ethylpyridinium Tetrafluoroborate

  • CAS No.878-23-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 2-Bromo-1-ethylpyridinium Tetrafluoroborate (CAS 878-23-9) for efficient organic condensation reactions. Reliable supply for pharmaceutical synthesis.

Request Bulk Pricing

Product Technical Details

Product Overview

2-Bromo-1-ethylpyridinium Tetrafluoroborate represents a cornerstone reagent in the field of advanced organic synthesis. Designed specifically for demanding condensation reactions, this pyridinium salt offers superior activation capabilities for carboxylic acids. In the competitive landscape of pharmaceutical manufacturing and fine chemical production, the reliability of your reagents directly impacts the efficiency and yield of your final products. Our grade of this compound is engineered to meet the rigorous standards required by global research institutions and industrial production facilities.

The unique structural configuration of this molecule allows it to function as a potent electrophilic activator. By facilitating the formation of reactive intermediates, it enables chemists to construct complex molecular architectures with precision. Whether used in the development of new therapeutic candidates or the scale-up of established processes, this reagent provides the consistency needed to minimize variability. We prioritize the production of this chemical under strict Good Manufacturing Practices (GMP) guidelines to ensure that every batch meets the specified purity thresholds.

Technical Specifications

Transparency and accuracy in chemical specifications are vital for process validation. We provide comprehensive data for each lot to support your quality control procedures. The table below outlines the critical physical and chemical properties associated with our standard supply:

ParameterSpecification
CAS Registry Number878-23-9
IUPAC Name2-Bromo-1-ethylpyridin-1-ium Tetrafluoroborate
Molecular FormulaC7H9BBrF4N
Molecular Weight273.86 g/mol
Physical AppearanceWhite Crystalline Powder
Assay (HPLC)≥98.0%
Melting Point Range102-104°C
SolubilitySoluble in Polar Organic Solvents

Industrial Applications

The primary utility of 2-Bromo-1-ethylpyridinium Tetrafluoroborate lies in its role as a condensation reagent. It is extensively employed in the synthesis of peptides, where the formation of amide bonds is a fundamental step. The reagent activates the carboxyl group, making it susceptible to nucleophilic attack by amines, thereby driving the coupling reaction forward with high efficiency. This capability is crucial for producing active pharmaceutical ingredients (APIs) where structural integrity is non-negotiable.

Beyond peptide synthesis, this compound is valuable in esterification processes and the modification of natural products. Its compatibility with various solvent systems allows for flexibility in process design. Manufacturers appreciate its ability to reduce reaction times and lower energy consumption compared to traditional methods. By integrating this reagent into your synthesis route, you can achieve cleaner reaction profiles with fewer by-products, simplifying the purification workflow and reducing overall production costs.

Quality Assurance and Advantages

Choosing the right supplier for critical synthesis reagents is a strategic decision. Our commitment to quality ensures that you receive a product that performs consistently across different scales of operation. We implement multi-stage testing protocols to verify identity, purity, and physical characteristics before release.

  • High Purity Guarantee: Minimum 98 percent purity ensures minimal interference in sensitive reactions.
  • Process Stability: Consistent physical properties support reproducible manufacturing outcomes.
  • Technical Support: Access to detailed safety data sheets and technical guidance for optimal usage.
  • Global Logistics: Efficient packaging and shipping solutions to maintain product integrity during transit.
  • Regulatory Compliance: Produced in facilities adhering to international chemical safety and quality standards.
  • Custom Packaging: Flexible drum sizes available to suit both laboratory trials and bulk production needs.

Storage and Handling Guidelines

Proper storage is essential to maintain the chemical stability of 2-Bromo-1-ethylpyridinium Tetrafluoroborate. The material should be kept in a cool, dry, and well-ventilated environment, protected from direct exposure to sunlight and moisture. Containers must be tightly sealed after each use to prevent absorption of atmospheric water, which could lead to hydrolysis. When handling this compound, appropriate personal protective equipment including gloves and safety goggles should be worn. In case of spills, follow standard chemical hygiene protocols for containment and cleanup. Adhering to these guidelines ensures the longevity of the product and the safety of your personnel.