2-Bromo-3,4-difluorobenzoic acid
- CAS No.170108-05-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Bromo-3,4-difluorobenzoic acid (CAS 170108-05-1) designed for advanced organic synthesis. Reliable supply with ≥99.0% purity for pharmaceutical and agrochemical intermediates.
Request Bulk PricingProduct Technical Details
Product Overview
2-Bromo-3,4-difluorobenzoic acid is a highly specialized fluorinated aromatic building block essential for modern medicinal chemistry and agrochemical development. As a critical intermediate, this compound features a unique substitution pattern that enables diverse synthetic transformations. The presence of both bromine and fluorine atoms on the benzoic acid scaffold provides exceptional reactivity for cross-coupling reactions, nucleophilic aromatic substitutions, and heterocycle formations. Our manufacturing process ensures consistent quality suitable for scaling from laboratory research to industrial production.
This chemical serves as a foundational component in the synthesis of complex pharmaceutical APIs and advanced functional materials. The strategic positioning of the halogen substituents allows chemists to introduce specific structural motifs required for enhancing biological activity or material performance. We prioritize strict quality control measures to guarantee that every batch meets the rigorous demands of downstream synthesis processes.
Key Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 2-Bromo-3,4-difluorobenzoic acid |
| CAS Number | 170108-05-1 |
| Molecular Formula | C7H3BrF2O2 |
| Molecular Weight | 236.998 g/mol |
| Purity (HPLC) | ≥99.0% |
| Appearance | Off white to faint peach powder |
| Density | 1.872 g/cm3 |
| Boiling Point | 292.9°C |
| Flash Point | 131°C |
| Refractive Index | 1.558 |
Industrial Applications
The primary utility of 2-Bromo-3,4-difluorobenzoic acid lies in its role as a versatile intermediate for organic synthesis. Pharmaceutical researchers utilize this compound to construct kinase inhibitors, receptor modulators, and other therapeutic agents where fluorine substitution improves metabolic stability and bioavailability. The bromine atom serves as an excellent handle for palladium-catalyzed coupling reactions, facilitating the creation of biaryl structures common in drug candidates.
In the agrochemical sector, this building block contributes to the development of novel herbicides and pesticides with improved environmental profiles. Additionally, it finds application in the synthesis of liquid crystals and organic electronic materials where precise halogen placement dictates physical properties. Our global clientele relies on this product for its reliability in multi-step synthesis routes requiring high fidelity and minimal impurity profiles.
Quality Assurance And Packaging
We maintain a robust quality management system to ensure product integrity from synthesis to delivery. Each production batch undergoes comprehensive testing using high-performance liquid chromatography and spectroscopic methods to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment, detailing all critical quality attributes. Our facility adheres to international safety standards for the handling and storage of fine chemicals.
Standard packaging consists of 25 kg drums lined with protective materials to prevent moisture uptake and contamination. Custom packaging solutions are available to meet specific logistical requirements or smaller scale research needs. Storage recommendations include keeping the material in a cool, ventilated area away from incompatible substances. We offer competitive bulk pricing and reliable global shipping options to support your supply chain efficiency. Contact our technical sales team for detailed manufacturing process information or custom synthesis inquiries.
