Intermediates

2-Bromo-3-chloro-5-fluoropyridine

  • CAS No.1214326-94-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 2-Bromo-3-chloro-5-fluoropyridine is a versatile halogenated heterocyclic intermediate designed for advanced pharmaceutical and agrochemical synthesis applications.

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Product Technical Details

Product Overview

2-Bromo-3-chloro-5-fluoropyridine is a highly specialized halogenated heterocyclic compound that serves as a critical building block in modern organic synthesis. Characterized by its unique substitution pattern on the pyridine ring, this molecule offers exceptional reactivity for nucleophilic aromatic substitution and transition metal-catalyzed cross-coupling reactions. Our manufacturing process ensures consistent quality and high purity, making it an ideal choice for research and industrial scale production.

The presence of multiple halogen atoms at specific positions allows chemists to selectively functionalize the pyridine core, facilitating the development of complex molecular architectures. This compound is particularly valued in the discovery and development of new active pharmaceutical ingredients and advanced agrochemical formulations.

Technical Specifications

ParameterValue
Chemical Name2-Bromo-3-chloro-5-fluoropyridine
CAS Number1214326-94-9
Molecular FormulaC5H2BrClFN
Molecular Weight210.43 g/mol
Purity≥99.0%
AppearanceWhite Crystalline Powder
Density1.8±0.1 g/cm3
Boiling Point200.2±35.0 °C at 760 mmHg
Flash Point74.9±25.9 °C

Industrial Applications

This versatile intermediate finds extensive use across multiple high-value sectors. In the pharmaceutical industry, it acts as a key precursor for synthesizing kinase inhibitors and other therapeutic agents targeting neurological and oncological pathways. The specific halogen arrangement supports Suzuki, Buchwald, and Sonogashira coupling reactions, enabling precise molecular engineering.

In agrochemical development, this compound contributes to the creation of next-generation pesticides and herbicides with improved environmental profiles. Additionally, it serves as a valuable intermediate in the production of specialty dyes and flavoring agents where specific heterocyclic structures are required for performance and stability.

Quality Assurance and Storage

We adhere to strict quality control protocols to ensure every batch meets international standards. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) verifying purity and physical properties. Proper handling is essential to maintain product integrity.

  • Store in well-closed, light-resistant, and airtight containers.
  • Maintain in a cool, dry, and well-ventilated area away from incompatible materials.
  • Available in 25kg drums or customized packaging based on client requirements.
  • Global shipping capabilities ensure timely delivery for production schedules.

Our commitment to safety and compliance ensures that this chemical intermediate is supplied with all necessary documentation for regulatory adherence in your jurisdiction.