Intermediates

2-Bromo-3-fluorobenzaldehyde

  • CAS No.891180-59-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Bromo-3-fluorobenzaldehyde (CAS 891180-59-9) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical and agrochemical intermediates.

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Product Technical Details

Product Overview

2-Bromo-3-fluorobenzaldehyde represents a critical class of fluorinated building blocks essential for modern medicinal chemistry and advanced material science. As a specialized aromatic aldehyde featuring both bromine and fluorine substituents on the benzene ring, this compound offers unique reactivity profiles that enable diverse synthetic transformations. Our manufacturing process ensures consistent quality suitable for large-scale industrial applications, meeting the rigorous demands of global chemical supply chains.

The strategic placement of the bromo and fluoro groups allows chemists to exploit orthogonal reactivity during multi-step synthesis. This molecule serves as a versatile precursor where the aldehyde functionality can be modified through reduction, oxidation, or condensation reactions, while the halogen substituents facilitate metal-catalyzed cross-coupling processes. We maintain strict production standards to guarantee batch-to-batch consistency.

Technical Specifications

ParameterValue
Chemical Name2-Bromo-3-fluorobenzaldehyde
CAS Number891180-59-9
Molecular FormulaC7H4BrFO
Molecular Weight203.01 g/mol
Purity (GC)≥98.0%
AppearanceWhite to light yellow crystal powder
Density1.67 g/cm3
Boiling Point227.4 °C
Flash Point91.3 °C

Industrial Applications

This intermediate serves as a key precursor in the synthesis of various pharmaceutical agents, particularly those requiring fluorinated aromatic cores to enhance metabolic stability and bioavailability. The presence of the bromine atom facilitates cross-coupling reactions such as Suzuki or Buchwald-Hartwig couplings, while the aldehyde group allows for further functionalization. Beyond pharmaceuticals, this compound is utilized in the development of agrochemicals and fine chemicals.

  • Pharmaceutical intermediates for novel drug discovery
  • Agrochemical synthesis for crop protection agents
  • Liquid crystal materials for display technologies
  • Fine chemical production for specialized polymers

Quality Assurance And Storage

We adhere to strict quality control protocols throughout the manufacturing lifecycle. Each production batch undergoes comprehensive analytical testing using gas chromatography and other advanced methods to verify purity and identity. Every shipment is accompanied by a Certificate of Analysis (COA) to ensure transparency and compliance with international standards. Our logistics team ensures secure packaging to maintain product integrity during transit.

For optimal stability, store this material in a cool, ventilated place away from direct sunlight and moisture. Keep containers tightly closed when not in use. Avoid contact with strong oxidizing agents to prevent unintended reactions. Our team provides technical support to assist with safe handling procedures and integration into your specific synthesis routes. We offer flexible packaging options including 25 kg drums or custom configurations based on client requirements to support both pilot-scale and full-scale production needs.