Intermediates

2-Bromo-3-methylbutyric acid

  • CAS No.565-74-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Bromo-3-methylbutyric acid (CAS 565-74-2) designed for advanced organic synthesis applications. Available in bulk quantities with comprehensive quality documentation.

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Product Technical Details

Product Overview

2-Bromo-3-methylbutyric acid, also known commercially as DL-2-Bromoisovaleric acid, is a specialized brominated carboxylic acid serving as a critical building block in modern organic synthesis. This compound is characterized by its alpha-bromo functionality, which enables versatile chemical transformations essential for the development of complex pharmaceutical intermediates and agrochemical agents. Our manufacturing process ensures consistent quality and high purity levels, making it a reliable choice for research and industrial scale production.

As a key intermediate, this substance plays a pivotal role in constructing carbon skeletons and introducing functional groups during multi-step synthesis routes. The presence of the bromine atom at the alpha position facilitates nucleophilic substitution reactions, allowing chemists to derive a wide array of downstream derivatives. We prioritize strict quality control measures to guarantee that every batch meets the rigorous demands of medicinal chemistry and process development teams.

Chemical Properties and Specifications

The physical and chemical characteristics of 2-Bromo-3-methylbutyric acid are optimized for stability and handling in standard laboratory and plant environments. It typically presents as a crystalline solid with a distinct melting range, ensuring ease of weighing and dissolution in common organic solvents. The high purity grade provided minimizes side reactions during sensitive coupling processes, thereby improving overall yield and reducing purification burdens.

ParameterSpecification
CAS Number565-74-2
Molecular FormulaC5H9BrO2
Molecular Weight181.03 g/mol
AppearanceWhite to beige crystalline powder or solid
Purity (GC)≥98.0%
Melting Point39-42°C
Boiling Point124-126°C
Density1.513 g/cm³
Refractive Index1.479

Industrial Applications

This brominated fatty acid derivative is extensively utilized in the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals. Its primary application lies in serving as an electrophilic partner in alkylation reactions or as a precursor for generating organometallic reagents. In the agrochemical sector, it contributes to the formation of herbicides and pesticides requiring specific branched-chain structures. Furthermore, it is valued in academic research for exploring new catalytic cycles and reaction mechanisms involving alpha-halo acids.

  • Essential intermediate for pharmaceutical drug discovery
  • Precursor for agrochemical active ingredients
  • Reagent for organic method development
  • Building block for complex molecule synthesis

Quality Assurance and Safety

We adhere to international quality management standards to ensure product integrity. Each shipment is accompanied by a Certificate of Analysis (COA) detailing batch-specific test results. Proper storage is essential to maintain stability; the product should be kept in a cool, ventilated area away from incompatible materials such as strong oxidizers or bases. Our packaging options are designed to protect the material from moisture and light during transit, ensuring it arrives in optimal condition for immediate use.