2-Bromo-3-methylthiophene
- CAS No.14282-76-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 2-Bromo-3-methylthiophene (CAS 14282-76-9) designed for pharmaceutical synthesis. Reliable supply for Tiagabine intermediate production with strict quality control.
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Product Overview
2-Bromo-3-methylthiophene is a specialized heterocyclic organic compound widely utilized in the pharmaceutical and fine chemical industries. As a key brominated thiophene derivative, this substance serves as a critical building block for the synthesis of complex molecular structures. Our manufacturing process ensures high chemical stability and consistency, making it an ideal choice for research and development teams focused on advanced organic synthesis.
This compound features a thiophene ring substituted with a bromine atom and a methyl group, providing unique reactivity profiles suitable for cross-coupling reactions. The precise positioning of functional groups allows chemists to efficiently construct larger pharmacophores required for modern therapeutic agents.
Technical Specifications
We adhere to strict quality control protocols to guarantee that every batch meets international standards. The following table outlines the key physical and chemical properties verified during our quality assurance process.
| Parameter | Specification |
|---|---|
| CAS Number | 14282-76-9 |
| Molecular Formula | C5H5BrS |
| Molecular Weight | 177.062 g/mol |
| Appearance | Light yellow transparent liquid |
| Assay (Purity) | ≥99.0% |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 177.3±20.0 °C at 760 mmHg |
| Flash Point | 68.3±0.0 °C |
Industrial Applications
The primary application of 2-Bromo-3-methylthiophene lies in the synthesis of pharmaceutical intermediates. It is notably used in the production pathway of Tiagabine hydrochloride, an important anticonvulsant agent. The bromine functionality facilitates palladium-catalyzed coupling reactions, such as Suzuki or Stille couplings, enabling the formation of carbon-carbon bonds essential for drug molecule assembly.
Beyond pharmaceuticals, this chemical serves as a versatile intermediate in the development of agrochemicals and functional materials. Its high purity level ensures minimal side reactions during synthesis, improving overall yield and reducing downstream purification costs for our clients.
Quality Assurance and Storage
Quality is paramount in our production facility. Each batch undergoes rigorous testing using advanced analytical techniques including Gas Chromatography (GC) and Nuclear Magnetic Resonance (NMR) to confirm identity and purity. A Certificate of Analysis (COA) is provided with every shipment to document compliance with specified parameters.
For optimal stability, the product should be stored in a cool, ventilated place away from direct sunlight and moisture. Containers must remain tightly sealed when not in use to prevent oxidation or contamination. We offer flexible packaging options, including 25 kg drums, and can customize packaging solutions based on specific customer logistics requirements. Our global supply chain ensures timely delivery while maintaining product integrity throughout transit.
