2-Bromo-3-nitropyridine
- CAS No.19755-53-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Bromo-3-nitropyridine (CAS 19755-53-4) is a critical heterocyclic intermediate designed for advanced organic synthesis and pharmaceutical manufacturing processes.
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Product Overview
2-Bromo-3-nitropyridine serves as a pivotal building block in the realm of heterocyclic chemistry, specifically tailored for complex organic synthesis pathways. This compound features a pyridine ring substituted with both bromo and nitro functional groups, creating a highly reactive platform for nucleophilic substitution and cross-coupling reactions. Our manufacturing facility produces this chemical intermediate with stringent quality controls to ensure consistency and reliability for downstream applications in the pharmaceutical and agrochemical industries.
The strategic positioning of the bromine and nitro groups on the pyridine ring allows chemists to perform selective transformations, making it an invaluable asset for developing new molecular entities. Whether utilized in medicinal chemistry research or large-scale production, this material provides the foundational structure necessary for constructing more complex heterocyclic systems.
Technical Specifications
We adhere to rigorous analytical standards to guarantee the quality of every batch. The following table outlines the key physical and chemical properties verified through our quality assurance protocols:
| Parameter | Specification |
|---|---|
| Chemical Name | 2-Bromo-3-nitropyridine |
| CAS Number | 19755-53-4 |
| Molecular Formula | C5H3BrN2O2 |
| Molecular Weight | 202.99 g/mol |
| Appearance | Yellow powder |
| Purity | ≥99.0% |
| Melting Point | 122-125°C |
| Boiling Point | 244°C |
| Density | 1.833 g/cm³ |
| Flash Point | 101.4°C |
| Refractive Index | 1.614 |
Industrial Applications
As a versatile intermediate, this compound finds extensive utility across multiple sectors. Its primary application lies in the synthesis of pharmaceutical active ingredients where heterocyclic motifs are prevalent. The reactivity of the bromo group facilitates palladium-catalyzed coupling reactions, while the nitro group can be reduced to an amine for further functionalization.
- Pharmaceutical Intermediate: Used in the development of novel therapeutic agents targeting various disease states.
- Agrochemical Synthesis: Serves as a precursor for specialized pesticides and herbicides requiring pyridine structures.
- Material Science: Employed in the creation of advanced organic materials and functional polymers.
- Research and Development: Essential for academic and industrial laboratories focusing on heterocyclic chemistry.
Quality Assurance and Packaging
Every shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing the test results against our internal specifications. We utilize robust packaging methods to maintain product integrity during transit. Standard packaging consists of 25 kg drums, though we offer flexible solutions to meet specific customer requirements. Our logistics team ensures timely delivery while complying with all international shipping regulations for chemical goods.
Storage and Handling
To preserve the stability and quality of 2-Bromo-3-nitropyridine, proper storage conditions are essential. The material should be kept in a cool, ventilated area away from direct sunlight and moisture. Containers must remain tightly sealed when not in use to prevent contamination or degradation. Personnel handling this chemical should follow standard safety procedures, including the use of appropriate personal protective equipment such as gloves and safety goggles. By adhering to these guidelines, users can ensure safe and effective utilization of this high-performance chemical intermediate.
