2-Bromo-4'-chloroacetophenone
- CAS No.536-38-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Bromo-4'-chloroacetophenone (CAS 536-38-9) designed for professional pharmaceutical synthesis. Reliable supply with strict quality control for global industrial partners.
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Product Overview
2-Bromo-4'-chloroacetophenone is a highly specialized organic compound serving as a critical building block in advanced chemical synthesis. Recognized by its CAS registry number 536-38-9, this substance is engineered to meet the rigorous demands of modern pharmaceutical and industrial manufacturing processes. Our facility produces this intermediate under strict quality assurance protocols to ensure consistent molecular integrity and performance across various downstream applications.
The chemical structure combines bromine and chlorine substituents on an acetophenone backbone, providing unique reactivity profiles essential for complex organic transformations. This specific arrangement allows chemists to utilize the compound effectively in nucleophilic substitution reactions and condensation processes. We understand that purity is paramount in multi-step synthesis pathways, which is why our production lines are optimized to minimize impurities and by-products.
Technical Specifications
To guarantee reliability for our B2B partners, every batch undergoes comprehensive analytical testing. The following table outlines the key physical and chemical properties that define our standard grade material. These parameters are critical for process engineers when designing reaction conditions and safety protocols.
| Property | Specification |
|---|---|
| Chemical Formula | C8H6BrClO |
| Molecular Weight | 233.49 g/mol |
| CAS Number | 536-38-9 |
| Appearance | White to light yellow solid |
| Purity | Greater than or equal to 99.0 percent |
| Melting Point | 95 to 99 degrees Celsius |
| Boiling Point | 289.7 degrees Celsius at 760 mmHg |
| Density | 1.598 g/cm3 |
| Moisture Content | Less than or equal to 0.50 percent |
Industrial Applications
This compound is primarily utilized as a versatile intermediate in the synthesis of complex organic molecules. Its stability and reactivity make it suitable for producing active pharmaceutical ingredients (APIs) and fine chemicals. Specifically, it serves as a key precursor in the manufacturing pathway for certain cardiovascular therapeutic agents, including intermediates related to Tolvaptan synthesis. Researchers value this material for its ability to facilitate efficient coupling reactions while maintaining high yield rates.
Beyond pharmaceuticals, 2-Bromo-4'-chloroacetophenone finds utility in broader organic synthesis projects where halogenated ketones are required. The presence of both bromo and chloro groups offers synthetic flexibility, allowing for selective functionalization at different positions on the aromatic ring. This versatility supports innovation in drug discovery and material science sectors.
Quality Assurance and Safety
As a responsible global manufacturer, we prioritize safety and compliance in every shipment. Each order is accompanied by a Certificate of Analysis (COA) verifying that the product meets stated specifications. Our quality control team employs advanced chromatography and spectroscopy methods to validate purity levels before release. This commitment ensures that your production processes remain uninterrupted and compliant with regulatory standards.
Regarding handling, the material should be stored in a cool, ventilated warehouse away from direct heat sources and open flames. The storage temperature should not exceed 37 degrees Celsius to maintain stability. Proper personal protective equipment is recommended during handling to prevent exposure. We package the product in 250kg barrels by default, though custom packaging solutions are available to meet specific logistical requirements. Our export team manages all hazardous material documentation, including HS codes and UN numbers, to ensure smooth international customs clearance.
