Intermediates

2-Bromo-4-chlorobenzaldehyde

  • CAS No.84459-33-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Bromo-4-chlorobenzaldehyde (CAS 84459-33-6) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for pharmaceutical and chemical manufacturing.

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Product Technical Details

Product Overview

2-Bromo-4-chlorobenzaldehyde is a highly specialized halogenated aromatic compound that serves as a critical building block in modern organic chemistry. Characterized by its unique substitution pattern on the benzene ring, this molecule offers exceptional reactivity for various coupling reactions and functional group transformations. Our facility produces this compound under strict quality control standards to ensure consistency for downstream pharmaceutical and agrochemical applications.

As a key intermediate, this benzaldehyde derivative is engineered to meet the rigorous demands of complex synthesis routes. The presence of both bromine and chlorine substituents provides versatile handles for cross-coupling reactions, making it an invaluable asset for medicinal chemists and process development teams seeking to construct sophisticated molecular architectures.

Technical Specifications

ParameterSpecification
Chemical Name2-Bromo-4-chlorobenzaldehyde
CAS Number84459-33-6
Molecular FormulaC7H4BrClO
Molecular Weight219.46 g/mol
AppearanceWhite to light yellow solid
Assay (Purity)≥98.0%
Moisture Content≤1.0%
Density1.698 g/cm3
Boiling Point264.6 °C
Flash Point113.8 °C
Refractive Index1.623

Industrial Applications

This compound is primarily utilized as a precursor in the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals. Its structural properties allow it to participate efficiently in Suzuki, Heck, and other palladium-catalyzed coupling reactions. Researchers frequently employ this material in the development of novel therapeutic agents where specific halogen positioning is required for biological activity.

Beyond pharmaceuticals, 2-Bromo-4-chlorobenzaldehyde finds utility in the production of advanced agrochemicals and functional materials. The high purity grade we supply ensures minimal impurity profiles, which is crucial for preventing side reactions during multi-step synthesis processes. This reliability helps our partners optimize yields and reduce waste in their manufacturing operations.

Quality Assurance and Manufacturing

We adhere to international quality management systems to guarantee the integrity of every batch. Each production lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR spectroscopy, to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment, documenting compliance with the specified parameters.

  • Consistent batch-to-batch reproducibility
  • Strict control over halogen content and isomer distribution
  • Low heavy metal and residual solvent levels
  • Full traceability from raw materials to finished goods

Storage and Handling

To maintain optimal stability, 2-Bromo-4-chlorobenzaldehyde should be stored in a cool, ventilated place away from direct sunlight and moisture. The material is packaged in 25 kg drums, though custom packaging solutions are available to meet specific logistical requirements. Proper handling procedures should be followed in accordance with safety data sheets to ensure workplace safety during transfer and usage.

Our global logistics network ensures timely delivery to industrial partners worldwide. For technical inquiries or custom synthesis requests regarding this intermediate, our expert team is available to provide detailed support and formulation guidance.