2-Bromo-4-fluoroanisole
- CAS No.452-08-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Bromo-4-fluoroanisole (CAS 452-08-4) is a vital fluorinated building block designed for complex organic synthesis and pharmaceutical intermediate manufacturing.
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Product Overview
2-Bromo-4-fluoroanisole represents a critical component in the realm of advanced organic synthesis, serving as a versatile fluorinated building block for pharmaceutical and agrochemical development. This aromatic ether combines the reactivity of a bromine substituent with the electronic influence of a fluorine atom, making it an indispensable precursor for cross-coupling reactions and nucleophilic substitutions. Our manufacturing facility ensures that every batch meets rigorous international standards, providing researchers and industrial clients with a reliable source of high-quality chemical intermediates.
The compound is characterized by its stable liquid form and distinct chemical properties that facilitate seamless integration into multi-step synthesis routes. As a trusted global manufacturer, we prioritize consistency and purity, understanding that the success of downstream applications depends heavily on the quality of the starting materials. Whether utilized in the creation of novel therapeutic agents or specialized functional materials, this product delivers the performance required for demanding chemical processes.
Key Specifications
| Parameter | Value |
|---|---|
| CAS Number | 452-08-4 |
| Molecular Formula | C7H6BrFO |
| Molecular Weight | 205.024 g/mol |
| Appearance | Colorless transparent liquid |
| Assay | ≥98.0% |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 273.6±0.0 °C at 760 mmHg |
| Flash Point | 98.3±0.0 °C |
| Refractive Index | 1.519 |
Industrial Applications
This fluorinated intermediate finds extensive utility across multiple sectors of the chemical industry. Its primary application lies in the synthesis of complex pharmaceutical APIs, where the introduction of fluorine atoms can significantly enhance metabolic stability and bioavailability. The bromine functionality allows for palladium-catalyzed coupling reactions, enabling the construction of biaryl structures common in modern drug discovery. Additionally, it serves as a key reagent in the production of agrochemicals, liquid crystals, and advanced polymeric materials.
- Pharmaceutical intermediate synthesis for neurological and cardiovascular therapeutics.
- Agrochemical development requiring fluorinated aromatic structures.
- Material science applications involving liquid crystal displays.
- Custom organic synthesis projects demanding high-purity building blocks.
Quality Assurance and Storage
We maintain a comprehensive quality control system that includes strict testing protocols for identity, purity, and physical constants. Each shipment is accompanied by a Certificate of Analysis (COA) to verify compliance with specified parameters. To maintain optimal stability, the product should be stored in a cool, ventilated area away from direct sunlight and incompatible materials. Our packaging options include 200 kg drums, with flexibility to accommodate specific customer requirements for bulk orders. By choosing our supply chain, clients gain access to industrial purity levels and consistent manufacturing processes that support large-scale production needs.
