Intermediates

2-Bromo-4-fluorobenzaldehyde

  • CAS No.59142-68-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Bromo-4-fluorobenzaldehyde (CAS 59142-68-6) designed for advanced organic synthesis. Reliable supply with ≥99.0% purity for pharmaceutical and agrochemical intermediates.

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Product Technical Details

Product Overview

2-Bromo-4-fluorobenzaldehyde is a highly specialized organic intermediate characterized by its unique halogenated aromatic structure. This fluorinated benzaldehyde derivative serves as a critical building block in the synthesis of complex pharmaceutical compounds and agrochemical agents. Our facility produces this chemical under strict quality control standards to ensure consistent molecular integrity and performance in downstream reactions.

As a key member of the halogenated aromatic aldehyde family, this compound offers excellent reactivity profiles suitable for nucleophilic substitution and coupling reactions. The presence of both bromine and fluorine substituents on the benzene ring provides versatile sites for functionalization, making it an indispensable resource for medicinal chemistry and process research organizations.

Technical Specifications

ParameterValue
Chemical Name2-Bromo-4-fluorobenzaldehyde
CAS Number59142-68-6
Molecular FormulaC7H4BrFO
Molecular Weight203.01 g/mol
Purity (GC)≥99.0%
AppearanceWhite to light yellow powder
Melting Point61.5°C
Boiling Point234.9°C
Density1.7 g/cm³

Industrial Applications

This intermediate is primarily utilized in the manufacturing of active pharmaceutical ingredients (APIs) and fine chemicals. Its specific substitution pattern allows for targeted synthesis pathways in the development of novel therapeutic agents. Common applications include:

  • Synthesis of kinase inhibitors and other targeted cancer therapies.
  • Production of fluorinated agrochemicals for crop protection.
  • Development of liquid crystals and advanced material precursors.
  • Use in cross-coupling reactions such as Suzuki or Buchwald-Hartwig processes.

Quality Assurance and Safety

We adhere to rigorous quality management systems to guarantee product consistency. Every batch undergoes comprehensive testing via gas chromatography and nuclear magnetic resonance to verify identity and purity. A Certificate of Analysis (COA) is provided with each shipment to ensure compliance with your internal specifications.

For safety, this compound should be handled in a well-ventilated environment using appropriate personal protective equipment. It must be stored in a cool, dry place away from incompatible materials to maintain stability. Our packaging options include 25 kg drums or custom solutions tailored to logistical requirements.