Intermediates

2-Bromo-4-fluoronitrobenzene

  • CAS No.700-36-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Bromo-4-fluoronitrobenzene (CAS 700-36-7) designed for advanced organic synthesis and pharmaceutical intermediate manufacturing.

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Product Technical Details

Product Overview

2-Bromo-4-fluoronitrobenzene is a highly specialized fluorinated aromatic intermediate essential for modern organic synthesis. Characterized by the presence of both bromine and nitro functional groups on a fluorinated benzene ring, this compound serves as a versatile building block in the production of complex pharmaceutical agents and agrochemical formulations. Our manufacturing process ensures exceptional purity levels, making it an ideal choice for research and industrial-scale applications where consistency and reliability are paramount.

As a key member of the halogenated nitrobenzene family, this chemical exhibits unique reactivity profiles that facilitate nucleophilic aromatic substitution reactions. The strategic positioning of the fluorine and bromine atoms allows chemists to selectively functionalize the molecule, enabling the construction of diverse molecular architectures required in drug discovery and material science. We prioritize quality control at every stage of production to deliver a product that meets rigorous international standards.

Technical Specifications

ParameterValue
Chemical Name2-Bromo-4-fluoronitrobenzene
CAS Number700-36-7
Molecular FormulaC6H3BrFNO2
Molecular Weight219.996 g/mol
AppearanceLight green to yellow solid
Assay (Purity)≥98.0%
Melting Point44°C
Boiling Point224.0±20.0 °C at 760 mmHg
Density1.8±0.1 g/cm3
Flash Point89.3±21.8 °C
Refractive Index1.580

Industrial Applications

This intermediate is predominantly utilized in the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals. The fluorine atom enhances metabolic stability and bioavailability in drug candidates, while the bromine and nitro groups provide handles for further chemical modification. Common applications include the development of kinase inhibitors, anti-inflammatory agents, and specialized polymers. Additionally, it serves as a precursor in the agrochemical sector for creating herbicides and pesticides with improved environmental profiles.

  • Pharmaceutical intermediate for targeted therapy drugs
  • Building block for fluorinated organic compounds
  • Reagent for nucleophilic substitution reactions
  • Precursor in agrochemical formulation development
  • Material science applications for advanced polymers

Storage and Handling

To maintain optimal quality, 2-Bromo-4-fluoronitrobenzene should be stored in a cool, ventilated area away from direct sunlight and moisture. Containers must be kept tightly sealed when not in use to prevent degradation or contamination. Proper personal protective equipment (PPE), including gloves and safety goggles, is recommended during handling to ensure safety. We offer flexible packaging options, including 25 kg drums, and can customize packaging solutions to meet specific logistical requirements for global shipment.