Intermediates

2-Bromo-4-fluorophenol

  • CAS No.496-69-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Bromo-4-fluorophenol (CAS 496-69-5) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for pharmaceutical and agrochemical intermediates.

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Product Technical Details

Product Overview

2-Bromo-4-fluorophenol is a highly specialized halogenated aromatic compound that serves as a critical building block in modern organic chemistry. Manufactured under strict quality control standards, this chemical features a unique substitution pattern that enables versatile reactivity in cross-coupling reactions and nucleophilic substitutions. Our facility produces this intermediate using advanced bromination and fluorination techniques to ensure consistent batch-to-batch reliability. The compound is particularly valued for its stability and high reactivity profile, making it an essential precursor for complex molecular architectures in the pharmaceutical and agrochemical sectors.

We understand the importance of purity in synthetic pathways. Therefore, our production process includes multiple purification steps to remove residual solvents and by-products. This commitment to quality ensures that downstream reactions proceed with minimal interference, optimizing yield and reducing waste in your manufacturing processes. As a global manufacturer, we are dedicated to supplying research laboratories and industrial plants with materials that meet rigorous international standards.

Technical Specifications

The following table outlines the key physical and chemical properties of our 2-Bromo-4-fluorophenol. These parameters are verified through advanced analytical methods including HPLC, GC-MS, and NMR spectroscopy. We provide a Certificate of Analysis (COA) with every shipment to guarantee compliance with the specified assay and physical characteristics.

ParameterSpecification
CAS Number496-69-5
Molecular FormulaC6H4BrFO
Molecular Weight190.998 g/mol
AppearanceOff-white powder
Assay (Purity)≥98.0%
Melting Point43-45 °C
Boiling Point260.6 °C at 760 mmHg
Density1.8±0.1 g/cm3
Flash Point85.0 °C

Industrial Applications

This fluorinated phenol derivative is primarily utilized as an intermediate in the synthesis of biologically active compounds. Its structural properties allow for selective functionalization, which is crucial in the development of new drug candidates. In the pharmaceutical industry, it is often employed in the preparation of kinase inhibitors and receptor modulators where specific halogen placement is required for binding affinity. Additionally, the compound finds application in agrochemical synthesis, contributing to the development of herbicides and pesticides with improved environmental profiles.

Beyond life sciences, 2-Bromo-4-fluorophenol is used in the production of specialized polymers and liquid crystal materials. The presence of both bromine and fluorine atoms offers unique electronic properties that enhance the performance of final materials in optoelectronic applications. Our technical team can provide guidance on optimal reaction conditions for various synthetic routes, ensuring that you achieve the best results in your specific application context.

Storage and Safety

Proper handling and storage are essential to maintain the integrity of this chemical. The product should be stored in a cool, ventilated area away from direct sunlight and moisture. Containers must be kept tightly closed when not in use to prevent oxidation or contamination. We recommend using appropriate personal protective equipment (PPE) including gloves and safety goggles during handling. For detailed safety information, please refer to the Material Safety Data Sheet (MSDS) provided with your order.

Quality Assurance and Logistics

As a leading global manufacturer, we prioritize supply chain reliability. Our packaging options include 25 kg drums, with custom packaging available upon request to suit specific logistical needs. We offer worldwide shipping with secure packaging to ensure the product arrives in perfect condition. Every batch undergoes rigorous testing before release, and we maintain full traceability from raw materials to finished goods. Contact our sales team today for bulk pricing, sample requests, or technical consultations regarding your synthesis requirements.