(2-Bromo-4-fluorophenyl)methanol
- CAS No.229027-89-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity (2-Bromo-4-fluorophenyl)methanol serves as a vital fluorinated building block for advanced pharmaceutical and agrochemical synthesis processes.
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Product Overview
(2-Bromo-4-fluorophenyl)methanol, also known commercially as 2-Bromo-4-fluorobenzyl Alcohol, is a specialized fluorinated organic intermediate designed for complex chemical synthesis. This compound features a unique substitution pattern with both bromine and fluorine atoms on the benzyl ring, making it an invaluable precursor in modern medicinal chemistry and material science. The presence of the fluorine atom enhances metabolic stability and lipophilicity in downstream pharmaceutical candidates, while the bromine moiety provides a reactive handle for various cross-coupling reactions.
Our manufacturing facility produces this chemical intermediate under strict quality control standards to ensure consistent batch-to-batch reliability. We understand that researchers and industrial clients require materials with high purity levels to minimize side reactions during multi-step synthesis. Therefore, each production run undergoes rigorous analytical testing to verify structural integrity and purity specifications before release.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 229027-89-8 |
| Molecular Formula | C7H6BrFO |
| Molecular Weight | 205.02 g/mol |
| Assay (Purity) | ≥98.0% |
| Density | 1.658 g/cm3 |
| Boiling Point | 262.3 °C |
| Flash Point | 112.4 °C |
| Refractive Index | 1.566 |
Industrial Applications
This fluorinated benzyl alcohol derivative is primarily utilized as a key building block in the synthesis of active pharmaceutical ingredients (APIs). Chemists leverage the reactivity of the bromine atom to perform Suzuki-Miyaura or Buchwald-Hartwig couplings, enabling the construction of complex biaryl structures common in kinase inhibitors and receptor modulators. Additionally, the hydroxymethyl group allows for further functionalization into esters, ethers, or halides, expanding its utility in diverse synthetic routes.
Beyond pharmaceuticals, this intermediate finds applications in agrochemical development where fluorinated compounds are prized for their enhanced biological activity and environmental stability. Material scientists also explore these structures for creating specialized polymers and liquid crystals. Our team supports clients with technical data packages to facilitate smooth integration into your specific manufacturing processes.
Quality Assurance and Handling
We maintain a robust quality management system to guarantee the integrity of our chemical products. Every shipment is accompanied by a Certificate of Analysis (COA) detailing the test results against our internal specifications. We recommend storing this product in a cool, ventilated area away from direct sunlight and incompatible materials. Proper handling procedures should be followed according to standard safety data sheets to ensure workplace safety.
- High purity grade suitable for sensitive synthetic reactions
- Stable supply chain with global manufacturing capabilities
- Flexible packaging options to meet diverse industrial needs
- Comprehensive technical support and documentation provided
For large-scale procurement or custom synthesis requirements, our sales team is available to discuss volume pricing and logistics. We are committed to supporting innovation in the chemical industry by providing reliable, high-quality intermediates that meet the demanding standards of modern research and production.
