2-Bromo-4-fluoropyridine
- CAS No.357927-50-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Bromo-4-fluoropyridine (CAS 357927-50-5) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for pharmaceutical and agrochemical manufacturing.
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Product Overview
2-Bromo-4-fluoropyridine is a highly valued heterocyclic building block extensively utilized in modern organic synthesis and medicinal chemistry. As a halogenated pyridine derivative, this compound serves as a critical intermediate for constructing complex molecular architectures. Our manufacturing facility produces this chemical with stringent quality controls to ensure consistent performance in downstream reactions. The presence of both bromine and fluorine substituents on the pyridine ring offers unique reactivity profiles, enabling selective cross-coupling and nucleophilic substitution reactions.
We understand the importance of reliability in the supply chain for research and production scales. Therefore, our 2-Bromo-4-fluoropyridine is synthesized using advanced industrial processes that maximize yield while minimizing impurities. This commitment to quality makes it an ideal choice for pharmaceutical companies, agrochemical developers, and material science researchers who require precise chemical properties for their formulations.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 357927-50-5 |
| Molecular Formula | C5H3BrFN |
| Molecular Weight | 175.986 |
| Appearance | Colorless liquid |
| Assay | ≥98.0% |
| Moisture Content | ≤0.5% |
| Density | 1.7±0.1 g/cm3 |
| Boiling Point | 188.8±20.0 °C at 760 mmHg |
| Flash Point | 68.0±21.8 °C |
Industrial Applications
The versatility of 2-Bromo-4-fluoropyridine allows it to function as a key precursor in various high-value industries. In the pharmaceutical sector, it is frequently employed in the synthesis of kinase inhibitors and other therapeutic agents targeting neurological or metabolic disorders. The fluorine atom enhances metabolic stability, while the bromine site facilitates palladium-catalyzed coupling reactions such as Suzuki or Buchwald-Hartwig couplings.
- Pharmaceutical Intermediate: Used in drug discovery and active pharmaceutical ingredient (API) synthesis.
- Agrochemical Development: Serves as a building block for novel pesticides and herbicides.
- Material Science: Utilized in the creation of specialized polymers and electronic materials.
- Research Reagent: Essential for academic and industrial laboratories focusing on heterocyclic chemistry.
Quality Assurance and Storage
Every batch of 2-Bromo-4-fluoropyridine undergoes rigorous testing to verify compliance with specified parameters. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing purity levels and physical properties. Our packaging options include 200 kg drums, with flexibility to accommodate custom requirements based on client logistics and volume needs.
Proper storage is essential to maintain product integrity. We recommend storing this chemical in a cool, ventilated area away from direct sunlight and moisture sources. Containers should remain tightly sealed when not in use to prevent degradation. Our global logistics network ensures timely delivery while adhering to all safety regulations for hazardous materials transport. Contact our technical support team for detailed safety data sheets and formulation guidance.
