Intermediates

2-Bromo-4'-methylacetophenone

  • CAS No.619-41-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Bromo-4'-methylacetophenone (CAS 619-41-0) designed for advanced pharmaceutical synthesis and organic research applications.

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Product Technical Details

Product Overview

2-Bromo-4'-methylacetophenone, identified by CAS number 619-41-0, stands as a critical building block in the realm of fine chemical synthesis and pharmaceutical development. This alpha-bromo ketone derivative is characterized by its high reactivity, making it an indispensable reagent for constructing complex molecular architectures. Our manufacturing process ensures that every batch meets stringent purity standards, specifically tailored for researchers and industrial chemists who require reliability and consistency in their synthetic pathways.

As a specialized intermediate, this compound facilitates various nucleophilic substitution reactions, enabling the efficient introduction of functional groups into organic frameworks. The presence of the bromine atom at the alpha position relative to the carbonyl group enhances its electrophilic character, allowing for versatile transformations in multi-step synthesis protocols. We prioritize quality control at every stage of production to deliver a product that supports high-yield reactions and minimizes downstream purification challenges.

Technical Specifications

ParameterSpecification
Product Name2-Bromo-4'-methylacetophenone
CAS Number619-41-0
Molecular FormulaC9H9BrO
Molecular Weight213.07 g/mol
AppearanceWhite to light yellow crystal powder
Purity≥99.0%
Moisture Content≤0.20%
Melting Point45-49 °C
Boiling Point238-239 °C
Density0.993 g/mL at 25 °C
Refractive Indexn20/D 1.528

Industrial Applications

This chemical intermediate finds extensive utility across multiple sectors of the chemical industry. Primarily, it serves as a key precursor in the synthesis of pharmaceutical active ingredients, where precise molecular modification is required. Organic chemists utilize this compound to develop novel therapeutic agents, leveraging its reactive bromine moiety for coupling reactions and structural elaboration.

Beyond pharmaceuticals, 2-Bromo-4'-methylacetophenone is employed in the creation of agrochemicals and specialty materials. Its stability under standard storage conditions and compatibility with various solvents make it a preferred choice for laboratory-scale research and large-scale manufacturing processes. Whether used in heterocyclic synthesis or as a starting material for fine chemicals, this product delivers consistent performance that aligns with industrial expectations for quality and efficiency.

Quality Assurance and Safety

We adhere to rigorous quality management systems to ensure that all shipped products comply with international safety and purity standards. Each batch is accompanied by a comprehensive Certificate of Analysis (COA), verifying parameters such as purity, moisture content, and physical constants. Our quality assurance team conducts regular audits and testing to maintain the integrity of our supply chain.

Regarding safety, this substance should be handled with appropriate personal protective equipment. It is stable under recommended conditions but is incompatible with strong oxidizing agents and strong bases. Storage should be maintained in a cool, ventilated warehouse, keeping the temperature below 37 °C and away from sources of ignition. Proper handling procedures ensure the safety of personnel and the preservation of product quality during transit and storage.

Packaging and Logistics

To accommodate diverse customer needs, we offer flexible packaging solutions. The standard packaging configuration is 250kg per barrel, ensuring secure transport for bulk orders. However, we understand that specific projects may require customized quantities, and we are fully equipped to package according to client requirements. Our logistics network supports global shipping, ensuring timely delivery while maintaining compliance with international hazardous material regulations, including proper UN classification and hazard labeling.