Intermediates

2-Bromo-4-Trifluoromethoxyaniline

  • CAS No.175278-17-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

2-Bromo-4-Trifluoromethoxyaniline is a high-purity fluorinated intermediate designed for complex organic synthesis. Reliable supply with full quality documentation.

Request Bulk Pricing

Product Technical Details

Product Overview

2-Bromo-4-Trifluoromethoxyaniline represents a critical fluorinated building block within the realm of advanced organic synthesis. As a specialized intermediate, this compound is engineered to meet the rigorous demands of pharmaceutical and agrochemical research laboratories. The incorporation of the trifluoromethoxy group enhances metabolic stability and lipophilicity, making it a preferred choice for medicinal chemists designing next-generation therapeutic agents. Our manufacturing process ensures consistent quality and high purity levels suitable for scale-up production.

Key Specifications

ParameterSpecification
Chemical Name2-Bromo-4-Trifluoromethoxyaniline
CAS Number175278-17-8
Molecular FormulaC7H5BrF3NO
Molecular Weight256.02 g/mol
AppearanceLight yellow to orange-yellow clear liquid
Assay (Purity)≥98.0%
Moisture Content≤0.5%
Density1.693 g/cm3
Boiling Point209°C
Flash Point>230°F

Industrial Applications

This fluorinated aniline derivative serves as a versatile precursor in the synthesis of complex heterocyclic compounds. It is extensively utilized in the development of novel pharmaceutical APIs, particularly where enhanced bioavailability is required. The bromine substituent allows for further functionalization via palladium-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings. Additionally, this intermediate finds application in the agrochemical sector for creating robust crop protection agents. Researchers value this material for its reactivity profile and stability under standard laboratory conditions.

Quality Assurance and Manufacturing

Our facility adheres to strict quality management systems to guarantee product integrity. Every batch of 2-Bromo-4-Trifluoromethoxyaniline undergoes comprehensive analytical testing using HPLC and GC-MS to verify purity and identity. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring transparency and compliance with international standards. Our production capabilities support both small-scale research quantities and large industrial volumes, maintaining consistent specifications across all batch sizes. Continuous monitoring of raw materials and final products minimizes impurities and ensures reliable performance in downstream synthesis.

Packaging and Storage

To maintain stability and safety, the product is packaged in secure drums suitable for hazardous chemical transport. Standard packaging includes 200 kg drums, though custom packaging solutions are available upon request to meet specific logistical requirements. Storage should be in a cool, well-ventilated area away from direct sunlight and incompatible materials. Proper handling procedures must be followed to ensure safety during transfer and usage. We offer global shipping services with comprehensive documentation to facilitate smooth customs clearance and timely delivery to your facility.