Intermediates

2-Bromo-4-(Trifluoromethoxy)benzonitrile

  • CAS No.1214334-83-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Bromo-4-(Trifluoromethoxy)benzonitrile designed for advanced organic synthesis and pharmaceutical intermediate applications.

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Product Technical Details

Product Overview

2-Bromo-4-(Trifluoromethoxy)benzonitrile is a sophisticated fluorinated organic compound that serves as a critical building block in modern medicinal chemistry and agrochemical development. Characterized by the presence of both a bromine substituent and a trifluoromethoxy group on the benzonitrile scaffold, this molecule offers unique reactivity profiles that are highly valued in complex synthesis routes. The trifluoromethoxy moiety is particularly notable for enhancing lipophilicity and metabolic stability in downstream pharmaceutical candidates, making this intermediate a preferred choice for research and development teams focusing on novel therapeutic agents.

Our manufacturing process ensures exceptional batch-to-batch consistency, adhering to strict quality control protocols suitable for large-scale industrial applications. As a dedicated supplier of specialty fine chemicals, we understand the importance of purity and reliability in your synthesis workflow. This product is supplied with comprehensive documentation, including Certificates of Analysis (COA), to facilitate regulatory compliance and quality assurance within your facility.

Technical Specifications

ParameterValue
Chemical Name2-Bromo-4-(Trifluoromethoxy)benzonitrile
CAS Number1214334-83-4
Molecular FormulaC8H3BrF3NO
Molecular Weight266.015 g/mol
AppearanceWhite to light yellow crystalline powder
Assay (Purity)≥98.0%
Density1.8±0.1 g/cm3
Boiling Point265.4±40.0 °C at 760 mmHg
Flash Point114.3±27.3 °C
Refractive Index1.515

Industrial Applications

This fluorinated nitrile derivative is primarily utilized as a key intermediate in the synthesis of complex organic molecules. Its structural features allow for versatile functionalization through cross-coupling reactions, nucleophilic substitutions, and other transformation processes common in process chemistry. Pharmaceutical companies leverage this compound to introduce fluorine atoms into drug candidates, a strategy often employed to improve bioavailability and binding affinity. Additionally, it finds application in the development of advanced materials and agrochemical formulations where specific electronic properties are required.

  • Essential building block for pharmaceutical API synthesis.
  • Used in the development of novel agrochemical active ingredients.
  • Suitable for research in organic electronic materials.
  • Supports custom synthesis projects requiring fluorinated scaffolds.

Quality Assurance and Storage

We prioritize the integrity of our chemical products throughout the supply chain. Each batch undergoes rigorous analytical testing to confirm identity and purity levels before release. To maintain optimal stability, 2-Bromo-4-(Trifluoromethoxy)benzonitrile should be stored in a cool, ventilated area away from direct sunlight and moisture. Standard packaging involves 25 kg drums, though we offer flexible packaging solutions tailored to specific customer requirements and logistics needs. Our global distribution network ensures timely delivery while maintaining compliance with international shipping regulations for chemical goods.