Intermediates

2-Bromo-4-(trifluoromethyl)pyridine

  • CAS No.175205-81-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Bromo-4-(trifluoromethyl)pyridine (CAS 175205-81-9) designed for advanced organic synthesis. Available in bulk quantities with full COA documentation.

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Product Technical Details

Product Overview

2-Bromo-4-(trifluoromethyl)pyridine is a highly specialized fluorinated heterocyclic compound that serves as a critical building block in modern organic synthesis. Characterized by its unique structural combination of a bromine substituent and a trifluoromethyl group on the pyridine ring, this chemical offers exceptional reactivity for various cross-coupling reactions. Our manufacturing process ensures consistent quality and high purity, making it an ideal choice for research and industrial applications requiring precise chemical performance.

As a leading global manufacturer, we prioritize strict quality control measures at every stage of production. This compound is extensively utilized in the development of advanced materials, agrochemicals, and pharmaceutical intermediates. The presence of the trifluoromethyl group enhances metabolic stability and lipophilicity, which are desirable traits in many downstream chemical products. We commit to providing reliable supply chains and technical support for all our clients.

Technical Specifications

ParameterValue
CAS Number175205-81-9
Molecular FormulaC6H3BrF3N
Molecular Weight225.994 g/mol
AppearanceOff-white crystalline powder
Assay (Purity)≥98.0%
Density1.7±0.1 g/cm3
Boiling Point195.9±35.0 °C at 760 mmHg
Flash Point72.3±25.9 °C
Refractive Index1.471

Industrial Applications

This fluorinated pyridine derivative is primarily employed as a key intermediate in complex organic synthesis pathways. Its chemical structure allows for versatile functionalization through palladium-catalyzed coupling reactions, nucleophilic substitutions, and lithiation processes. Researchers and process chemists value this compound for its ability to introduce both halogen and fluorine motifs into molecular scaffolds efficiently.

  • Used in the synthesis of novel pharmaceutical candidates where metabolic stability is crucial.
  • Employed in agrochemical development for creating robust active ingredients.
  • Utilized in material science for producing specialized polymers and liquid crystals.
  • Serves as a reference standard for analytical chemistry and quality control laboratories.

Storage and Packaging

To maintain optimal stability and purity, 2-Bromo-4-(trifluoromethyl)pyridine should be stored in a cool, ventilated area away from direct sunlight and moisture. Proper sealing is essential to prevent degradation or contamination. We offer flexible packaging solutions to meet diverse client needs, typically supplying in 25 kg drums. Custom packaging options are available upon request to facilitate safe transportation and handling. Each batch is accompanied by a Certificate of Analysis (COA) to verify compliance with specified quality standards.