Intermediates

2-Bromo-5-chloroanisole

  • CAS No.174913-09-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Bromo-5-chloroanisole (CAS 174913-09-8) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical and chemical manufacturing.

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Product Technical Details

Product Overview

2-Bromo-5-chloroanisole is a specialized halogenated aromatic compound widely recognized for its versatility in modern organic synthesis. As a critical building block, this chemical serves as a foundational element in the construction of complex molecular architectures required by the pharmaceutical and agrochemical industries. Our manufacturing process ensures that each batch meets rigorous international standards, providing researchers and industrial partners with a reliable source of high-quality intermediates. The compound features a methoxy group alongside bromine and chlorine substituents, offering unique reactivity profiles suitable for various coupling reactions and functional group transformations.

Technical Specifications

We maintain strict control over the physical and chemical properties of 2-Bromo-5-chloroanisole to guarantee consistency across all production lots. The material is characterized by its distinct thermal stability and solubility parameters, which are essential for downstream processing. Our quality assurance team utilizes advanced analytical techniques, including gas chromatography and nuclear magnetic resonance, to verify composition and purity levels. The following table outlines the key technical parameters associated with this product:

ParameterValue
CAS Number174913-09-8
Molecular FormulaC7H6BrClO
Molecular Weight221.48 g/mol
AppearanceWhite to yellow solid
Assay≥98.0%
Density1.564 g/cm3
Boiling Point236.6°C
Flash Point96.9°C
Moisture Content≤0.2%

Quality Assurance and Manufacturing

Our facility operates under a comprehensive quality management system designed to minimize impurities and maximize yield. Every production run undergoes multiple stages of inspection, from raw material sourcing to final packaging. We understand that trace impurities can significantly impact subsequent reaction steps in pharmaceutical synthesis. Therefore, we prioritize industrial purity levels that exceed standard market expectations. Customers receive a detailed Certificate of Analysis (COA) with every shipment, documenting specific batch data including spectral analysis and purity metrics. This transparency fosters trust and ensures seamless integration into your manufacturing workflows.

Industrial Applications

The primary application of 2-Bromo-5-chloroanisole lies in its role as an organic synthesis intermediate. It is frequently employed in the development of active pharmaceutical ingredients (APIs), where halogenated anisoles serve as precursors for kinase inhibitors and other therapeutic agents. Additionally, this compound finds utility in the agrochemical sector for the production of specialized pesticides and herbicides. The presence of both bromine and chlorine atoms allows for selective functionalization, enabling chemists to construct diverse molecular libraries. Whether used in cross-coupling reactions or nucleophilic substitutions, this material provides a robust platform for innovation in chemical research and development.

Storage and Handling

To maintain the integrity of 2-Bromo-5-chloroanisole, proper storage conditions are essential. The product should be kept in a cool, ventilated area away from direct sunlight and sources of ignition. Containers must remain tightly sealed to prevent moisture absorption, which could affect the specified moisture content levels. We recommend handling this material in accordance with standard safety protocols for halogenated organic compounds, including the use of appropriate personal protective equipment. Our packaging options include 25 kg drums, with flexibility to accommodate custom requirements based on volume needs. By adhering to these guidelines, customers can ensure the long-term stability and performance of the chemical in their respective applications.