Intermediates

2-Bromo-5-chlorobenzotrifluoride

  • CAS No.344-65-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Bromo-5-chlorobenzotrifluoride (CAS 344-65-0) designed for pharmaceutical and pesticide synthesis. Reliable supply for global industrial applications.

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Product Technical Details

Product Overview

2-Bromo-5-chlorobenzotrifluoride is a highly specialized fluorinated aromatic compound that serves as a critical building block in modern organic synthesis. Characterized by its unique substitution pattern featuring bromine, chlorine, and a trifluoromethyl group on the benzene ring, this intermediate offers exceptional reactivity for cross-coupling reactions and nucleophilic substitutions. Our manufacturing process ensures consistent quality, making it an ideal choice for research and industrial scale production.

As a leading supplier in the fine chemicals sector, we understand the importance of purity and reliability. This colorless liquid is processed under strict quality control standards to meet the rigorous demands of downstream applications. The presence of the trifluoromethyl moiety enhances metabolic stability and lipophilicity in final products, which is particularly valuable in the development of advanced agrochemicals and pharmaceutical agents.

Technical Specifications

ParameterValue
CAS Number344-65-0
Molecular FormulaC7H3BrClF3
Molecular Weight259.45 g/mol
Purity≥98.0%
AppearanceColorless liquid

Physical and Chemical Properties

The physical characteristics of 2-Bromo-5-chlorobenzotrifluoride are well-defined, facilitating easy handling in various synthetic routes. With a boiling point ranging between 179 and 180 degrees Celsius, it can be purified via distillation under standard or reduced pressure conditions. The density of 1.759 g/mL at 25 degrees Celsius indicates a heavy liquid phase, typical for halogenated aromatics. Additionally, the refractive index of 1.508 provides a reliable metric for identity confirmation during quality assurance testing. The flash point of 198 degrees Celsius suggests moderate flammability, requiring standard safety precautions during storage and transport.

Industrial Applications

This compound is predominantly utilized as a versatile intermediate in the synthesis of complex organic molecules. Its primary applications include:

  • Pharmaceutical Intermediates: Used in the construction of active pharmaceutical ingredients where fluorinated structures are required for enhanced bioavailability.
  • Agrochemical Synthesis: Serves as a precursor for high-performance pesticides and herbicides, leveraging the stability of the carbon-fluorine bond.
  • Dye and Pigment Industry: Employed in the production of specialized dyes requiring specific halogen substitution patterns for color fastness and stability.

Storage and Handling

To maintain optimal quality, 2-Bromo-5-chlorobenzotrifluoride should be stored in tightly closed containers within a cool, dry, and well-ventilated area. Protection from moisture and direct sunlight is recommended to prevent degradation. We offer flexible packing options, including 25kg fiber drums, to accommodate various logistical needs. Our global supply chain ensures timely delivery accompanied by comprehensive documentation, including Certificates of Analysis and safety data sheets. Commitment to safety and regulatory compliance remains our top priority for all chemical shipments.