2-Bromo-5-cyanopyridine

Product Overview

2-Bromo-5-cyanopyridine represents a critical class of halogenated heterocyclic compounds essential for modern medicinal chemistry and material science. As a specialized pyridine derivative, this substance features a unique substitution pattern that enables versatile synthetic transformations. Our company specializes in the production of high-quality chemical intermediates, ensuring that every batch meets stringent international standards for purity and performance. This product is designed to support research and development teams who require reliable raw materials for complex molecular construction.

The structural integrity of this bromopyridine allows it to serve as a robust precursor in multi-step synthesis pathways. The presence of the electron-withdrawing cyano group alongside the reactive bromine atom creates a balanced electronic environment on the aromatic ring. This balance is crucial for controlling regioselectivity during subsequent chemical modifications. We understand the demands of large-scale production and offer consistent quality to support your manufacturing timelines.

Physical And Chemical Properties

Understanding the physical characteristics of this intermediate is vital for safe handling and process optimization. The compound typically presents as an off-white to yellow powder, indicating high stability under standard storage conditions. With a molecular weight of approximately 183.01 g/mol, it possesses favorable solubility profiles in common organic solvents. The melting point range of 136-140°C confirms the crystalline nature of the material, which aids in purification processes such as recrystallization.

Industrial Applications And Reactivity

This chemical is predominantly utilized as a building block in the synthesis of pharmaceutical active ingredients and agrochemical compounds. The bromine substituent enables participation in palladium-catalyzed cross-coupling reactions, including Suzuki-Miyaura, Heck, and Sonogashira couplings. These reactions are fundamental for forming carbon-carbon bonds, allowing chemists to attach diverse aromatic or aliphatic groups to the pyridine core. Furthermore, the nitrile functionality can be hydrolyzed to carboxylic acids or reduced to amines, expanding the scope of possible derivatives.

• Development of kinase inhibitors and enzyme modulators.
• Synthesis of ligands for homogeneous catalysis.
• Production of functional materials and polymers.
• Creation of novel agrochemical active ingredients.

Quality Assurance And Supply Chain

Our commitment to quality ensures that every shipment of 2-Bromo-5-cyanopyridine is accompanied by a comprehensive Certificate of Analysis. We employ advanced analytical techniques to verify identity and purity, minimizing the risk of batch-to-batch variability. Our manufacturing process focuses on industrial purity and efficient synthesis route management to reduce impurities that could affect downstream reactions. Safety data sheets are available upon request to ensure compliant handling within your facility.

We offer flexible packaging solutions, including standard 25 kg drums or customized containers based on specific logistical needs. Storage recommendations advise keeping the product in a cool, ventilated place away from incompatible substances. Our global manufacturer network ensures timely delivery and competitive bulk price structures for long-term partners. Contact our sales team for detailed technical support and quotation regarding your specific project requirements.