2-Bromo-5-fluoroaniline
- CAS No.1003-99-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Bromo-5-fluoroaniline (CAS 1003-99-2) designed for pharmaceutical synthesis. Reliable supply with strict quality control.
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Product Overview
2-Bromo-5-fluoroaniline is a specialized halogenated aromatic amine that serves as a critical building block in modern organic synthesis and medicinal chemistry. Characterized by the presence of both bromine and fluorine substituents on the benzene ring, this compound offers unique reactivity profiles that are highly valued in the development of complex pharmaceutical agents. Our manufacturing process ensures consistent quality and high purity levels, making it an ideal choice for research and industrial scale applications.
The strategic positioning of the bromo and fluoro groups allows for versatile chemical transformations. This molecule is particularly effective in cross-coupling reactions, nucleophilic substitutions, and heterocycle formations. As a key intermediate, it facilitates the construction of diverse molecular architectures required for next-generation therapeutics. We adhere to strict production standards to guarantee that every batch meets the rigorous demands of the global pharmaceutical supply chain.
Key Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 2-Bromo-5-fluoroaniline |
| CAS Number | 1003-99-2 |
| Molecular Formula | C6H5BrFN |
| Molecular Weight | 190.01 g/mol |
| Appearance | Brown crystalline powder |
| Purity | ≥98.0% |
| Density | 1.694 g/cm3 |
| Melting Point | 43-47 °C |
| Boiling Point | 154 °C / 23mmHg |
| Flash Point | >230 °F |
| Refractive Index | 1.456 |
Industrial Applications
This compound is extensively utilized in the pharmaceutical industry as a precursor for various active pharmaceutical ingredients (APIs). The fluorine atom enhances metabolic stability and bioavailability in drug molecules, while the bromine atom provides a reliable handle for palladium-catalyzed coupling reactions. These features make 2-Bromo-5-fluoroaniline indispensable in the synthesis of kinase inhibitors, anti-inflammatory agents, and other specialized therapeutic classes.
Beyond pharmaceuticals, this chemical finds utility in agrochemical research and material science where functionalized anilines are required. Its stability under standard storage conditions and predictable reactivity profile allow chemists to design efficient synthetic routes with high yield outcomes. Our team supports clients with technical data to optimize integration into their specific manufacturing processes.
Quality Assurance and Storage
Quality is paramount in our production facility. Each batch of 2-Bromo-5-fluoroaniline undergoes comprehensive analytical testing including HPLC, GC-MS, and NMR spectroscopy to verify identity and purity. We provide a Certificate of Analysis (COA) with every shipment to ensure full transparency and compliance with international standards.
- Packaged in 25kg drums for secure and efficient transport.
- Store in a tightly closed container to prevent moisture absorption.
- Keep in a cool, dry, and well-ventilated area away from incompatible substances.
- Avoid exposure to direct sunlight and extreme temperatures.
- Handle with appropriate personal protective equipment during usage.
By choosing our products, you partner with a global manufacturer committed to safety, reliability, and chemical excellence. Contact us for bulk pricing and custom synthesis inquiries tailored to your project needs.
