2-Bromo-5-Fluoroanisole
- CAS No.450-88-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Bromo-5-Fluoroanisole (CAS 450-88-4) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical and agrochemical intermediates.
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Product Overview
2-Bromo-5-Fluoroanisole is a specialized halogenated aromatic ether designed for advanced organic synthesis applications. As a critical building block in modern medicinal chemistry, this compound features both bromine and fluorine substituents on the anisole ring, providing unique reactivity profiles for cross-coupling reactions and nucleophilic substitutions. Our manufacturing process ensures high consistency and purity, making it an ideal choice for research and development teams working on complex pharmaceutical intermediates and agrochemical formulations.
The strategic positioning of the fluoro and bromo groups allows chemists to exploit orthogonal reactivity, enabling selective functionalization during multi-step synthesis routes. This versatility makes the compound a valuable asset in the production of diverse chemical libraries and active pharmaceutical ingredients. We adhere to strict quality management systems to guarantee that every batch meets the rigorous demands of industrial scale production. The compound's solubility profile makes it compatible with various organic solvents, facilitating smooth reaction kinetics in homogeneous catalysis.
Key Specifications
Quality and precision are paramount in chemical manufacturing. The following table outlines the critical physical and chemical properties of our 2-Bromo-5-Fluoroanisole. These parameters are verified through advanced analytical techniques including gas chromatography and nuclear magnetic resonance spectroscopy to ensure compliance with international standards.
| CAS Number | 450-88-4 |
|---|---|
| Molecular Formula | C7H6BrFO |
| Molecular Weight | 205.024 g/mol |
| Appearance | Clear, pale lemony amber liquid |
| Assay | ≥98.0% |
| Density | 1.5±0.1 g/cm³ |
| Boiling Point | 187.9±20.0 °C at 760 mmHg |
| Flash Point | 80.2±6.0 °C |
| Refractive Index | 1.519 |
Industrial Applications
This fluorinated intermediate serves as a foundational component in the synthesis of various high-value compounds. Its primary utility lies in the pharmaceutical sector, where it acts as a precursor for developing novel therapeutic agents. The presence of the fluorine atom often enhances the metabolic stability and bioavailability of the final drug molecule, while the bromine atom facilitates palladium-catalyzed coupling reactions.
- Pharmaceutical Intermediate Synthesis
- Agrochemical Product Development
- Material Science and Polymer Modification
- Custom Organic Synthesis Projects
Beyond pharmaceuticals, this compound is utilized in the agrochemical industry to create potent crop protection agents. The stability of the ether linkage combined with the reactivity of the halogen substituents provides a robust platform for deriving new functional materials. Our supply chain is optimized to support both pilot-scale experiments and full commercial production runs. Furthermore, our technical support team is available to assist with process optimization and scale-up challenges.
Quality Assurance and Storage
We maintain a comprehensive quality assurance protocol that includes raw material inspection, in-process control, and final product verification. Each shipment is accompanied by a Certificate of Analysis (COA) to ensure transparency and compliance with international standards. Safety data sheets (SDS) are provided upon request to ensure safe handling procedures are followed throughout your facility.
Products should be stored in a cool, ventilated place away from direct sunlight and sources of ignition. Containers must be kept tightly closed when not in use to prevent moisture absorption or contamination. We offer flexible packaging options, including 200 kg drums, and can accommodate specific customer requirements for bulk logistics. Our global distribution network ensures timely delivery while maintaining safety regulations during transit.
