2-Bromo-5-fluoropyridine
- CAS No.41404-58-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 2-Bromo-5-fluoropyridine (CAS 41404-58-4) designed for pharmaceutical intermediate synthesis and advanced organic research applications.
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Product Overview
2-Bromo-5-fluoropyridine is a highly valued heterocyclic building block extensively utilized in the field of medicinal chemistry and organic synthesis. As a fluorinated pyridine derivative, this compound serves as a critical intermediate for constructing complex molecular architectures required in modern pharmaceutical development. Our facility specializes in the production of this chemical with stringent quality controls to ensure consistency across batches. The presence of both bromine and fluorine substituents on the pyridine ring offers versatile reactivity, enabling chemists to perform various cross-coupling reactions and nucleophilic substitutions efficiently.
We understand the demanding requirements of the pharmaceutical industry regarding purity and documentation. Therefore, every batch of 2-Bromo-5-fluoropyridine undergoes rigorous analytical testing. This product is particularly relevant for research into potential neurological therapeutics and other advanced clinical areas. By providing a reliable supply chain, we support our partners in accelerating their drug discovery pipelines while maintaining compliance with international safety and quality standards.
Technical Specifications
The following table outlines the key physical and chemical properties of our standard grade 2-Bromo-5-fluoropyridine. These parameters are essential for process engineers and research scientists to determine suitability for specific synthesis routes.
| Parameter | Value |
|---|---|
| CAS Number | 41404-58-4 |
| Molecular Formula | C5H3BrFN |
| Molecular Weight | 175.99 g/mol |
| Appearance | White crystal |
| Purity | ≥98.0% |
| Density | 1.7±0.1 g/cm3 |
| Melting Point | 30-31°C |
| Boiling Point | 171.6±20.0 °C at 760 mmHg |
| Flash Point | 57.6±21.8 °C |
| Refractive Index | 1.534 |
Industrial Applications
This fluorinated pyridine derivative is primarily employed as a key starting material in the synthesis of active pharmaceutical ingredients (APIs). Its unique substitution pattern allows for selective functionalization, making it indispensable in the development of compounds targeting specific biological receptors. In particular, it is used in the synthesis of intermediates for potential neurological therapeutics. Beyond pharmaceuticals, it finds utility in agrochemical research and material science where heterocyclic frameworks are required.
- Pharmaceutical intermediate for complex API synthesis
- Building block for cross-coupling reactions such as Suzuki or Buchwald
- Research reagent for developing neurological therapeutic candidates
- Component in advanced organic synthesis workflows
- Utilized in custom synthesis projects requiring high purity standards
Quality Assurance and Storage
Quality is the cornerstone of our manufacturing process. We implement a comprehensive Quality Management System that covers raw material sourcing, production monitoring, and final product verification. Each shipment is accompanied by a Certificate of Analysis (COA) detailing the test results against specified parameters. Proper storage is crucial to maintain the stability of 2-Bromo-5-fluoropyridine. The product should be stored in a tightly closed container in a cool, dry, and well-ventilated area away from incompatible substances. We recommend handling this chemical with appropriate personal protective equipment to ensure safety during laboratory or industrial use. Our logistics team ensures secure packaging, typically 25 KGS per drum, to prevent contamination or degradation during transit.
