Intermediates

2-Bromo-5-nitroanisole

  • CAS No.77337-82-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Bromo-5-nitroanisole (CAS 77337-82-7) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for pharmaceutical and chemical manufacturing.

Request Bulk Pricing

Product Technical Details

Product Overview

2-Bromo-5-nitroanisole, also known systematically as 1-Bromo-2-methoxy-4-nitrobenzene, is a specialized organic compound widely utilized in the field of fine chemical synthesis. As a critical building block, this brominated nitroanisole derivative serves as a fundamental intermediate for the construction of complex pharmaceutical molecules and agrochemical agents. Our manufacturing process ensures consistent quality and high purity levels, meeting the rigorous demands of modern industrial chemistry.

This compound features a unique substitution pattern on the benzene ring, combining bromine, methoxy, and nitro functional groups. This specific arrangement provides excellent reactivity for subsequent nucleophilic substitution or reduction reactions, making it an invaluable asset for research and development teams focused on new drug discovery and material science applications.

Technical Specifications

ParameterValue
Chemical Name2-Bromo-5-nitroanisole
CAS Number77337-82-7
Molecular FormulaC7H6BrNO3
Molecular Weight232.031 g/mol
AppearanceYellow crystalline powder
Assay (Purity)≥98.0%
Melting Point99-103 °C
Boiling Point302.1±22.0 °C at 760 mmHg
Density1.6±0.1 g/cm3
Flash Point136.5±22.3 °C
Refractive Index1.581

Industrial Applications

Primarily employed as an intermediate in organic synthesis, 2-Bromo-5-nitroanisole facilitates the production of various downstream derivatives. Its utility spans across several key sectors:

  • Pharmaceutical Industry: Used in the synthesis of active pharmaceutical ingredients (APIs) requiring specific aromatic substitution patterns.
  • Agrochemical Development: Serves as a precursor for herbicides and pesticides with targeted biological activity.
  • Fine Chemicals: Essential for creating specialized dyes, pigments, and functional materials.
  • Research Laboratories: Utilized in academic and industrial R&D for method development and structural elucidation.

Quality Assurance and Handling

We adhere to strict quality control protocols to ensure every batch meets the specified assay of ≥98.0%. Each shipment is accompanied by a Certificate of Analysis (COA) detailing comprehensive testing results. Proper handling is essential for safety and product integrity. The substance should be stored in a cool, ventilated area away from incompatible materials. Standard personal protective equipment (PPE) is recommended during handling to prevent inhalation or skin contact.

Packaging and Supply

To accommodate diverse industrial needs, we offer flexible packaging solutions. The standard package is 25 kg per drum, ensuring safe transport and storage. Custom packaging configurations are available upon request to align with specific logistical requirements. As a global manufacturer, we maintain a robust supply chain capable of delivering bulk quantities reliably. Contact our sales team for current bulk pricing, lead times, and sample availability.