Intermediates

2-Bromo-5-nitrobenzotrifluoride

  • CAS No.367-67-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Bromo-5-nitrobenzotrifluoride (CAS 367-67-9) designed for pharmaceutical synthesis. Reliable supply with strict quality control.

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Product Technical Details

Product Overview

2-Bromo-5-nitrobenzotrifluoride represents a cornerstone compound in the realm of fine chemical synthesis and pharmaceutical development. This aromatic organic molecule is characterized by the strategic placement of bromine, nitro, and trifluoromethyl functional groups on a benzene backbone. Such structural features impart unique electronic properties that are highly desirable for constructing complex molecular frameworks. Our facility produces this intermediate under strict quality management systems to ensure batch-to-batch consistency and high purity standards required by global clients. Furthermore, the stability of the nitro group allows for selective reduction steps in multi-step synthesis routes.

The incorporation of the trifluoromethyl group is particularly significant in medicinal chemistry. It often enhances the metabolic stability and lipophilicity of final drug products. Consequently, this material serves as a vital precursor for researchers aiming to optimize lead compounds. The electron-withdrawing effects of the substituents activate the ring for nucleophilic aromatic substitution, enabling versatile synthetic pathways. This reactivity profile makes it suitable for various coupling reactions used in the creation of novel therapeutic agents.

Technical Specifications

PropertyValue
CAS Number367-67-9
Molecular FormulaC7H3BrF3NO2
Molecular Weight270.00 g/mol
AppearancePale yellow crystal
Purity≥98.0%
Melting Point41-44 °C
Boiling Point87-88 °C (3 mm Hg)
Density1.788 g/mL at 25 °C

The physical properties of this compound are well-defined to assist in process optimization. The melting point range indicates high crystallinity, while the boiling point data supports distillation purification methods if required. Density and refractive index values are consistent with literature standards, confirming structural integrity. These parameters are rigorously tested using advanced analytical instrumentation before release.

Industrial Applications

In terms of industrial application, this chemical is predominantly utilized as a building block for active pharmaceutical ingredients. It is also relevant in the agrochemical sector for developing advanced crop protection solutions. The high purity specification of greater than 98 percent ensures minimal side reactions during downstream processing. We support our partners with reliable supply chains and technical documentation to facilitate smooth integration into their manufacturing processes. Customers benefit from our flexible packaging options which range from small laboratory scales to large industrial drums.

Quality Assurance and Storage

Our commitment to excellence extends beyond mere product delivery. We understand the critical nature of supply chain reliability in the pharmaceutical industry. Therefore, we maintain substantial inventory levels to accommodate urgent requests. Our technical team is available to provide guidance on usage and handling. We adhere to international regulatory standards to ensure compliance across different markets. This dedication makes us a preferred partner for long-term procurement strategies.

Safety and storage are paramount when handling reactive organic intermediates. The product should be maintained in a cool, dry environment away from incompatible materials. Proper ventilation and personal protective equipment are recommended during use. We provide fluorinated bottles or drums to ensure stability during transit. Each shipment includes a comprehensive Certificate of Analysis to verify identity and purity parameters.