Intermediates

2-Bromo-5-nitropyridine

  • CAS No.4487-59-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 2-Bromo-5-nitropyridine (CAS 4487-59-6) designed for advanced organic synthesis. Reliable supply for pharmaceutical and agrochemical intermediate production.

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Product Technical Details

Product Overview

2-Bromo-5-nitropyridine represents a critical heterocyclic building block within the realm of advanced organic synthesis. This compound features a pyridine core substituted with both bromo and nitro functional groups, which imparts unique chemical reactivity suitable for a wide range of transformation processes. As a specialized intermediate, it is extensively utilized by process chemists and researchers who require reliable materials for constructing complex molecular architectures. Our production facility focuses on delivering this chemical with exceptional consistency, ensuring that every batch meets the stringent requirements of modern pharmaceutical and agrochemical development pipelines. The strategic positioning of the substituents on the pyridine ring allows for selective reactions, making it a preferred choice for multi-step synthesis routes where precision is paramount.

Technical Specifications

We adhere to rigorous quality control protocols to guarantee the physical and chemical integrity of our products. The material is supplied as a distinct yellow powder, indicating its characteristic chemical state. Purity is verified using high-performance liquid chromatography to ensure levels exceed industry standards. Maintaining low moisture content is essential for preserving stability during storage and preventing unwanted hydrolysis during subsequent reactions. The following table outlines the key technical parameters that define our standard grade material.

ParameterValue
AppearanceYellow powder
Purity (HPLC)≥99.0%
Moisture≤0.5%
Melting Point139-141oC
Molecular FormulaC5H3BrN2O2

Industrial Applications

The primary application of this compound lies in its role as a versatile intermediate for organic synthesis. The presence of the bromine atom facilitates various cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, which are fundamental in creating carbon-carbon and carbon-nitrogen bonds. Additionally, the nitro group can be chemically modified through reduction or other transformations to introduce amino functionalities or other derivatives. This flexibility makes the product invaluable for the development of new active pharmaceutical ingredients and crop protection agents. Clients in the fine chemical sector rely on this material for its performance in creating high-value downstream products.

Quality Assurance and Storage

Quality assurance is embedded in every stage of our manufacturing process. Each production batch undergoes comprehensive testing, and a Certificate of Analysis is provided with every shipment to verify compliance with specifications. For optimal storage, the product should be kept in a cool and well-ventilated environment away from direct sunlight and incompatible substances. Proper packaging in sealed drums ensures protection from moisture and contamination during transit. We offer flexible packaging options to accommodate specific customer requirements, ranging from standard twenty-five kilogram drums to bulk orders. Safety handling procedures recommend the use of appropriate personal protective equipment to ensure a secure working environment during transfer and usage. Our logistics team ensures timely global delivery while maintaining chain of custody standards. We are committed to supporting our partners with technical data and regulatory documentation to facilitate smooth integration into your supply chain. Continuous improvement in our synthesis routes allows us to maintain competitive pricing without compromising on quality.