2-Bromo-5-(Trifluoromethyl)Benzaldehyde
- CAS No.875664-28-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Bromo-5-(Trifluoromethyl)Benzaldehyde for advanced organic synthesis. Reliable supply with COA and global shipping options.
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Product Overview
2-Bromo-5-(trifluoromethyl)benzaldehyde is a sophisticated fluorinated building block designed for complex organic synthesis applications. This compound features a unique structural arrangement where a bromine atom and a trifluoromethyl group are positioned on the benzaldehyde core. The presence of the trifluoromethyl moiety significantly enhances the lipophilicity and metabolic stability of downstream pharmaceutical or agrochemical products. As a key intermediate, it serves as a critical precursor in the development of novel therapeutic agents and functional materials.
Our manufacturing facility adheres to strict quality management systems to ensure consistent batch-to-batch reliability. We understand the critical nature of this chemical in multi-step synthesis routes, which is why we prioritize high purity levels and rigorous analytical testing. Whether used in academic research or large-scale industrial production, this material provides the foundational chemistry required for successful reaction outcomes.
Specifications and Physical Properties
The following table outlines the key physical and chemical parameters verified during our quality control process. Each batch is accompanied by a Certificate of Analysis (COA) to guarantee compliance with stated specifications.
| Parameter | Specification |
|---|---|
| CAS Number | 875664-28-1 |
| Molecular Formula | C8H4BrF3O |
| Molecular Weight | 253.02 g/mol |
| Appearance | Off-white to beige crystalline powder |
| Purity (GC) | ≥99.0% |
| Density | 1.677 g/cm3 |
| Boiling Point | 239.1 °C |
| Flash Point | 98.4 °C |
| Refractive Index | 1.511 |
Industrial Applications
This fluorinated aldehyde is primarily utilized as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and advanced organic materials. The bromine substituent allows for versatile cross-coupling reactions, such as Suzuki-Miyaura or Heck couplings, enabling chemists to construct complex biaryl structures efficiently. Furthermore, the electron-withdrawing nature of the trifluoromethyl group influences the reactivity of the aldehyde function, making it suitable for condensation reactions and reductive amination processes.
- Pharmaceutical Intermediate: Used in the development of kinase inhibitors and receptor modulators.
- Agrochemical Synthesis: Serves as a building block for novel herbicides and fungicides.
- Material Science: Employed in the creation of liquid crystals and organic electronic materials.
- Custom Synthesis: Available for bespoke research projects requiring specific isotopic labeling or derivative formation.
Quality Assurance and Storage
We maintain a robust quality assurance protocol that includes gas chromatography (GC) analysis for purity verification. Our facility ensures that all products are stored under optimal conditions to prevent degradation. Customers are advised to store this material in a cool, ventilated place away from direct sunlight and moisture. Proper storage ensures the longevity and stability of the chemical properties.
Packaging is available in 25 kg drums as standard, with flexible options to meet specific customer requirements. We offer global shipping services with comprehensive documentation to facilitate smooth customs clearance. For bulk orders, competitive pricing structures are available upon request. Contact our technical sales team for detailed information regarding lead times, safety data sheets, and custom packaging solutions.
