Intermediates

2-Bromo-6-fluorobenzoic acid

  • CAS No.2252-37-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Bromo-6-fluorobenzoic acid (CAS 2252-37-1) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical and agrochemical applications.

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Product Technical Details

Product Overview

2-Bromo-6-fluorobenzoic acid is a highly specialized halogenated aromatic compound that serves as a critical building block in modern organic synthesis. Identified by CAS number 2252-37-1, this chemical features a benzoic acid backbone substituted with both bromine and fluorine atoms at specific positions. This unique structural configuration imparts distinct reactivity profiles, making it an invaluable intermediate for the development of complex pharmaceutical agents, agrochemicals, and advanced functional materials.

Our manufacturing process ensures consistent quality and high purity levels suitable for demanding research and industrial applications. The presence of the fluorine atom enhances metabolic stability and lipophilicity in downstream products, while the bromine substituent offers a versatile handle for cross-coupling reactions. We adhere to strict production standards to guarantee that every batch meets the rigorous specifications required by global chemical industries.

Technical Specifications

The following table outlines the key physical and chemical properties of our 2-Bromo-6-fluorobenzoic acid. These parameters are verified through advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure accuracy and reliability for your synthesis protocols.

ParameterValue
Chemical Name2-Bromo-6-fluorobenzoic acid
CAS Number2252-37-1
Molecular FormulaC7H4BrFO2
Molecular Weight219.01 g/mol
AppearanceOff-white powder
Purity≥99.0%
Melting Point153-155°C
Boiling Point286.1°C
Density1.789 g/cm3
Flash Point126.8°C
Refractive Index1.567

Industrial Applications

This fluorinated benzoic acid derivative is primarily utilized as a key intermediate in the synthesis of biologically active compounds. In the pharmaceutical sector, it serves as a precursor for various drug candidates where the introduction of halogen atoms is necessary to modulate biological activity and pharmacokinetic properties. The compound is particularly useful in Suzuki and Heck coupling reactions, enabling chemists to construct complex molecular architectures efficiently.

Beyond pharmaceuticals, this material finds application in agrochemical development, where fluorinated structures are often employed to enhance pesticide efficacy and environmental stability. Additionally, it is used in material science for the creation of specialized polymers and liquid crystals. Our team supports customers with technical data and usage guidelines to optimize integration into their specific manufacturing processes.

Quality Assurance and Safety

Quality control is paramount in our production facility. Each batch of 2-Bromo-6-fluorobenzoic acid undergoes comprehensive testing to verify identity, purity, and impurity profiles. We provide a Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to safety extends to packaging and storage recommendations to maintain product integrity during transit.

  • Packaged in 25 kg drums or according to customer requirements.
  • Stored in a cool, ventilated area away from incompatible substances.
  • Handled with appropriate personal protective equipment during use.
  • Global shipping capabilities with compliant documentation.

We invite industrial partners and research institutions to contact us for bulk pricing, custom synthesis options, and detailed technical support. Our goal is to be your reliable partner in sourcing high-performance chemical intermediates.