2-Bromo-6-fluorobenzotrifluoride

Product Overview

2-Bromo-6-fluorobenzotrifluoride, identified by CAS number 261951-85-3, represents a critical fluorinated aromatic intermediate within the realm of advanced organic synthesis. This colorless liquid compound is engineered to meet the rigorous demands of modern medicinal chemistry and pharmaceutical development. As a specialized building block, it facilitates the construction of complex molecular architectures required for next-generation therapeutic agents. Our manufacturing process ensures consistent quality and reliability for both research and industrial scale applications, adhering to international safety and quality standards.

Recognized also by its synonym 1-Bromo-3-fluoro-2-(trifluoromethyl)benzene, this chemical exhibits stable physical properties suitable for various reaction conditions. The presence of both bromine and fluorine substituents on the benzene ring, along with the trifluoromethyl group, provides unique reactivity profiles essential for cross-coupling reactions and nucleophilic substitutions. We prioritize safety and purity in every batch produced, ensuring that researchers and production managers receive material that performs predictably in sensitive synthetic pathways.

Technical Specifications

Industrial Applications

This compound serves primarily as a pharmaceutical intermediate, enabling the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates. Its specific substitution pattern allows chemists to introduce fluorine and bromine functionalities selectively, which is crucial for optimizing metabolic stability and binding affinity in drug molecules. The trifluoromethyl group often enhances lipophilicity and bioavailability, making this intermediate highly valuable in the design of central nervous system and cardiovascular therapeutics. Beyond pharmaceuticals, it finds utility in agrochemical research and material science where fluorinated aromatics are required for performance enhancement.

• Key precursor for medicinal chemistry campaigns and drug discovery.
• Utilized in palladium-catalyzed coupling reactions such as Suzuki or Buchwald.
• Supports development of neurological and cardiovascular therapeutic agents.
• Compatible with diverse synthetic pathways and large-scale production processes.
• Essential for introducing fluorine atoms to improve metabolic stability.

Quality Assurance and Storage

We adhere to strict quality control protocols to ensure every drum meets the specified purity standards of ≥98.0%. Each shipment is accompanied by a Certificate of Analysis (COA) verifying physical and chemical properties through advanced analytical methods such as GC and HPLC. For optimal stability, the product should be stored in a tightly closed container within a cool, dry environment away from direct sunlight and incompatible materials. Proper handling procedures must be followed to maintain integrity during transport and usage, referencing the Safety Data Sheet (SDS) for comprehensive guidance.

Our packaging options include 25kg and 200kg drums, tailored to accommodate both laboratory-scale research and large-scale industrial production needs. As a global manufacturer, we provide reliable logistics support and competitive bulk pricing to support your supply chain efficiency. Contact our technical team for detailed synthesis routes, custom manufacturing inquiries, or to request samples for evaluation. We are committed to supporting your innovation with high-quality chemical solutions.