2-Bromo-6-fluorotoluene
- CAS No.1422-54-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Bromo-6-fluorotoluene (CAS 1422-54-4) designed for pharmaceutical and organic synthesis applications. Available in bulk quantities with strict quality control.
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Product Overview
2-Bromo-6-fluorotoluene is a specialized halogenated aromatic compound widely recognized for its utility in advanced organic synthesis and pharmaceutical manufacturing. As a key building block, this fluorinated toluene derivative facilitates the construction of complex molecular architectures required in modern medicinal chemistry. Our facility produces this intermediate under stringent quality management systems to ensure consistent performance in downstream reactions.
The compound features a unique substitution pattern with both bromine and fluorine atoms on the benzene ring, enabling selective cross-coupling reactions. This dual functionality makes it an invaluable reagent for chemists developing new active pharmaceutical ingredients (APIs) and agrochemical solutions. We commit to supplying material that meets or exceeds industry standards for purity and physical properties.
Key Specifications
Quality control is paramount in the production of fine chemical intermediates. Each batch undergoes rigorous testing using gas chromatography and other analytical methods to verify composition. The following table outlines the typical physical and chemical properties of our standard grade product.
| Parameter | Specification |
|---|---|
| CAS Number | 1422-54-4 |
| Molecular Formula | C7H6BrF |
| Molecular Weight | 189.02500 |
| Appearance | Colorless to yellow liquid |
| Purity | ≥98% |
| Water Content | ≤0.5% |
| Density | 1.53 g/cm3 |
| Boiling Point | 75-76°C at 10mmHg |
| Refractive Index | 1.535 |
| Flash Point | 76°C |
Industrial Applications
This fluorinated intermediate serves as a critical precursor in the synthesis of various therapeutic compounds. Its primary use lies in the formation of carbon-carbon and carbon-heteroatom bonds via palladium-catalyzed coupling reactions. The presence of the fluorine atom often enhances the metabolic stability and bioavailability of the final drug molecule, making this starting material highly sought after in drug discovery pipelines.
Beyond pharmaceuticals, 2-Bromo-6-fluorotoluene is utilized in the development of advanced materials and agrochemicals. Researchers leverage its reactivity to introduce specific functional groups into larger structures. Our manufacturing process ensures low levels of isomeric impurities, which is crucial for maintaining high yields in sensitive catalytic processes. We support clients ranging from academic research laboratories to large-scale commercial production facilities.
Quality Assurance and Packaging
We understand that consistency is vital for industrial processes. Every drum is accompanied by a Certificate of Analysis (COA) detailing the specific test results for that batch. Our quality assurance team monitors production from raw material sourcing to final packaging. The product is packed in secure plastic drums or plastic-coated iron drums, typically in 25kg units, to prevent contamination and ensure safety during transit.
Safety and Storage Guidelines
Proper handling is essential due to the chemical nature of this substance. It is classified under transport hazard class 6.1. Personnel should wear appropriate personal protective equipment, including chemical-resistant gloves and eye protection, when handling this material. Storage should be in a cool, dry, and well-ventilated area away from incompatible substances. Containers must be kept tightly closed when not in use to prevent moisture absorption and volatilization. We provide comprehensive safety data sheets (SDS) with every shipment to ensure compliance with local regulations.
