2-Bromo-N-methyl-N-(4-nitrophenyl)acetamide
- CAS No.23543-31-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate used in the synthesis of Nintedanib. Available in bulk quantities with strict quality control and comprehensive documentation.
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Product Overview
2-Bromo-N-methyl-N-(4-nitrophenyl)acetamide is a specialized organic compound characterized by its high chemical stability and reactivity profile suitable for complex pharmaceutical synthesis. Identified by CAS number 23543-31-9, this substance serves as a critical building block in the manufacturing of advanced therapeutic agents. Our production facilities adhere to rigorous international standards to ensure consistent quality and purity levels that meet the demanding requirements of the global pharmaceutical industry.
This intermediate is specifically engineered for use in multi-step organic synthesis pathways. The molecular structure, comprising a bromoacetyl group linked to a nitrophenyl moiety, facilitates specific coupling reactions essential for constructing larger pharmacologically active molecules. We prioritize safety and compliance in all handling and shipping procedures to maintain product integrity from our plant to your laboratory.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 2-Bromo-N-methyl-N-(4-nitrophenyl)acetamide |
| CAS Number | 23543-31-9 |
| Molecular Formula | C9H9BrN2O3 |
| Molecular Weight | 273.08 g/mol |
| Appearance | White solid |
| Purity | ≥99.0% |
| Density | 1.6 g/cm3 |
| Boiling Point | 387.2 °C at 760 mmHg |
| Flash Point | 188.0 °C |
Industrial Applications
The primary application of this chemical lies in the pharmaceutical sector, specifically as a key intermediate in the synthesis of Nintedanib. Nintedanib is a significant therapeutic agent used in the treatment of idiopathic pulmonary fibrosis and certain types of cancer. The precision required in producing such downstream medications demands upstream intermediates of exceptional purity and consistency. Our product is designed to integrate seamlessly into established synthesis routes, minimizing impurities that could affect final drug efficacy.
Beyond its specific role in Nintedanib production, this compound demonstrates versatility in organic chemistry research and development. It is suitable for laboratories focusing on the development of new kinase inhibitors and related therapeutic classes. We support both large-scale commercial manufacturing and smaller-scale research initiatives with flexible packaging options and technical support.
- Essential intermediate for Nintedanib esylate synthesis
- High reactivity for efficient coupling reactions
- Consistent batch-to-batch quality for regulatory compliance
- Compatible with standard industrial organic synthesis processes
Quality Assurance and Storage
Quality control is paramount in the production of pharmaceutical intermediates. Each batch of 2-Bromo-N-methyl-N-(4-nitrophenyl)acetamide undergoes comprehensive analytical testing, including HPLC and NMR spectroscopy, to verify identity and purity. We provide a Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with customer specifications. Our manufacturing processes are optimized to reduce environmental impact while maintaining high safety standards.
Proper storage is crucial to maintain the chemical properties of this product. It should be stored in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. Containers must remain tightly closed to prevent moisture absorption, which could degrade product quality. We recommend using standard personal protective equipment during handling. Our logistics team ensures secure packaging, typically in 25kg cardboard drums, though custom packaging solutions are available upon request to suit specific supply chain needs.
